ID   OFP16_ARATH             Reviewed;         244 AA.
AC   Q9SKY9; A1A6L2;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Transcription repressor OFP16;
DE   AltName: Full=Ovate family protein 16;
DE            Short=AtOFP16;
GN   Name=OFP16; OrderedLocusNames=At2g32100; ORFNames=F22D22.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   FUNCTION, TISSUE SPECIFICITY, GENE FAMILY, AND DISRUPTION PHENOTYPE.
RX   PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA   Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT   "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT   family, control multiple aspects of plant growth and development.";
RL   PLoS ONE 6:E23896-E23896(2011).
CC   -!- FUNCTION: Transcriptional repressor that regulates multiple aspects of
CC       plant growth and development through the regulation of BEL1-LIKE (BLH)
CC       and KNOX TALE (KNAT) homeodomain transcription factors.
CC       {ECO:0000269|PubMed:21886836}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, rosette and cauline leaves,
CC       shoots, stems, flower buds and siliques. {ECO:0000269|PubMed:21886836}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC       conditions. {ECO:0000269|PubMed:21886836}.
CC   -!- MISCELLANEOUS: Plants over-expressing OFP16 show small rosette size,
CC       late flowering, reduced fertilization and blunt-end siliques.
CC       {ECO:0000305|PubMed:21886836}.
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DR   EMBL; AC006223; AAD15394.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC08635.1; -; Genomic_DNA.
DR   EMBL; AF370597; AAK43916.1; -; mRNA.
DR   EMBL; BT029532; ABL66788.1; -; mRNA.
DR   PIR; A84729; A84729.
DR   RefSeq; NP_180770.1; NM_128770.3.
DR   AlphaFoldDB; Q9SKY9; -.
DR   BioGRID; 3117; 8.
DR   IntAct; Q9SKY9; 8.
DR   STRING; 3702.AT2G32100.1; -.
DR   PaxDb; Q9SKY9; -.
DR   PRIDE; Q9SKY9; -.
DR   ProteomicsDB; 250885; -.
DR   EnsemblPlants; AT2G32100.1; AT2G32100.1; AT2G32100.
DR   GeneID; 817770; -.
DR   Gramene; AT2G32100.1; AT2G32100.1; AT2G32100.
DR   KEGG; ath:AT2G32100; -.
DR   Araport; AT2G32100; -.
DR   TAIR; locus:2045472; AT2G32100.
DR   eggNOG; ENOG502S0CD; Eukaryota.
DR   HOGENOM; CLU_069722_1_0_1; -.
DR   InParanoid; Q9SKY9; -.
DR   OMA; CYSSPCI; -.
DR   OrthoDB; 1531622at2759; -.
DR   PhylomeDB; Q9SKY9; -.
DR   PRO; PR:Q9SKY9; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SKY9; baseline and differential.
DR   Genevisible; Q9SKY9; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR   InterPro; IPR038933; Ovate.
DR   InterPro; IPR006458; Ovate_C.
DR   PANTHER; PTHR33057; PTHR33057; 1.
DR   Pfam; PF04844; Ovate; 1.
DR   TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR   PROSITE; PS51754; OVATE; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..244
FT                   /note="Transcription repressor OFP16"
FT                   /id="PRO_0000429685"
FT   DOMAIN          166..235
FT                   /note="OVATE"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT   REGION          63..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          111..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..91
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        6
FT                   /note="W -> R (in Ref. 4; ABL66788)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   244 AA;  27062 MW;  E90EF7FF2ABB93E6 CRC64;
     MPKILWKSLH LCFPSNLTKC YSSPCIPPSS ADPDGIIQPN RPSIVLLNNF NLLYHNDNHH
     HPHRVIDLPS SSTTTTPAAT SSSSTSSYES DISPDVSAAF ASRRFFFSSP GRSNAITDSP
     EPRSREFSDN YDDATITSTK KKKKKVYDNS VTTTTTRLIS GGTAVTQHVD SPDPLTDFRR
     SMQEMIDAAI DAGELSRDPN DGYDFLDELL LTYLSLNPAD THKFVIRAFS DILVSLLSEE
     RRIC