OFP3_ARATH
ID OFP3_ARATH Reviewed; 296 AA.
AC Q9LVL4;
DT 09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Transcription repressor OFP3;
DE AltName: Full=Ovate family protein 3;
DE Short=AtOFP3;
GN Name=OFP3; OrderedLocusNames=At5g58360; ORFNames=MCK7.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP INTERACTION WITH BLH1; BLH3; KNAT5 AND KNAT7.
RX PubMed=15781858; DOI=10.1073/pnas.0501181102;
RA Hackbusch J., Richter K., Muller J., Salamini F., Uhrig J.F.;
RT "A central role of Arabidopsis thaliana ovate family proteins in networking
RT and subcellular localization of 3-aa loop extension homeodomain proteins.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:4908-4912(2005).
RN [5]
RP FUNCTION, AND GENE FAMILY.
RX PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT family, control multiple aspects of plant growth and development.";
RL PLoS ONE 6:E23896-E23896(2011).
CC -!- FUNCTION: Transcriptional repressor that may regulate multiple aspects
CC of plant growth and development through the regulation of BEL1-LIKE
CC (BLH) and KNOX TALE (KNAT) homeodomain transcription factors.
CC {ECO:0000269|PubMed:21886836}.
CC -!- SUBUNIT: Interacts with BLH1, BLH3, KNAT5 and KNAT7.
CC {ECO:0000269|PubMed:15781858}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- MISCELLANEOUS: Plants over-expressing OFP3 have no visible phenotype.
CC {ECO:0000305|PubMed:21886836}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AB019228; BAA96927.1; -; Genomic_DNA.
DR EMBL; CP002688; AED97042.1; -; Genomic_DNA.
DR EMBL; DQ056725; AAY78869.1; -; mRNA.
DR RefSeq; NP_200644.1; NM_125221.2.
DR AlphaFoldDB; Q9LVL4; -.
DR SMR; Q9LVL4; -.
DR BioGRID; 21192; 5.
DR IntAct; Q9LVL4; 4.
DR STRING; 3702.AT5G58360.1; -.
DR PaxDb; Q9LVL4; -.
DR PRIDE; Q9LVL4; -.
DR EnsemblPlants; AT5G58360.1; AT5G58360.1; AT5G58360.
DR GeneID; 835948; -.
DR Gramene; AT5G58360.1; AT5G58360.1; AT5G58360.
DR KEGG; ath:AT5G58360; -.
DR Araport; AT5G58360; -.
DR TAIR; locus:2161198; AT5G58360.
DR eggNOG; ENOG502RTS2; Eukaryota.
DR HOGENOM; CLU_036558_0_0_1; -.
DR InParanoid; Q9LVL4; -.
DR OMA; DIMPHSW; -.
DR OrthoDB; 1209787at2759; -.
DR PRO; PR:Q9LVL4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LVL4; baseline and differential.
DR Genevisible; Q9LVL4; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR025830; DNA_bnd_dom_ovate.
DR InterPro; IPR038933; Ovate.
DR InterPro; IPR006458; Ovate_C.
DR PANTHER; PTHR33057; PTHR33057; 1.
DR Pfam; PF13724; DNA_binding_2; 1.
DR Pfam; PF04844; Ovate; 1.
DR TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR PROSITE; PS51754; OVATE; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..296
FT /note="Transcription repressor OFP3"
FT /id="PRO_0000429672"
FT DOMAIN 228..287
FT /note="OVATE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT REGION 27..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..162
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 296 AA; 33440 MW; 1B126A666BB9E9B1 CRC64;
MKQKMGTHKF RFSDMMPHSW LYKLKGMSRS SRKHHLSSPK HLSSADASSS RKLRDPLRRL
SSTAHHPQAS NSPPKSSSFK RKIKRKTVYK PSSRLKLSTS SSLNHRSKSS SSANAISDSA
VGSFLDRVSS PSDQNFVHDP EPHSSIDIKD ELSVRKLDDV PEDPSVSPNL SPETAKEPPF
EMMTQQKLKK PKAHSSGIKI PTKIVRKKKK ERTSQVSKKK GVVKSFAIVL SSVDPEKDFR
ESMVEMIMEN KMREQKDLED LLACYLSLNS SEYHDVIIKA FENTWLHLTQ GLSISL
