OFP7_ARATH
ID OFP7_ARATH Reviewed; 315 AA.
AC Q9ZU65;
DT 09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Transcription repressor OFP7;
DE AltName: Full=Ovate family protein 7;
DE Short=AtOFP7;
GN Name=OFP7; OrderedLocusNames=At2g18500; ORFNames=F24H14.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, AND GENE FAMILY.
RX PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT family, control multiple aspects of plant growth and development.";
RL PLoS ONE 6:E23896-E23896(2011).
CC -!- FUNCTION: Transcriptional repressor that regulates multiple aspects of
CC plant growth and development through the regulation of BEL1-LIKE (BLH)
CC and KNOX TALE (KNAT) homeodomain transcription factors.
CC {ECO:0000269|PubMed:21886836}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, shoots, stems, flower buds and
CC siliques. {ECO:0000269|PubMed:21886836}.
CC -!- MISCELLANEOUS: Plants over-expressing OFP7 show kidney-shaped
CC cotyledons, round and curled leaves, small rosette size, late
CC flowering, reduced fertilization and round seeds.
CC {ECO:0000305|PubMed:21886836}.
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DR EMBL; AC006135; AAD12216.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06775.1; -; Genomic_DNA.
DR EMBL; BT002903; AAO22719.1; -; mRNA.
DR EMBL; BT004469; AAO42463.1; -; mRNA.
DR PIR; A84565; A84565.
DR RefSeq; NP_179440.1; NM_127406.3.
DR AlphaFoldDB; Q9ZU65; -.
DR BioGRID; 1722; 3.
DR IntAct; Q9ZU65; 3.
DR STRING; 3702.AT2G18500.1; -.
DR iPTMnet; Q9ZU65; -.
DR PaxDb; Q9ZU65; -.
DR PRIDE; Q9ZU65; -.
DR ProteomicsDB; 238928; -.
DR EnsemblPlants; AT2G18500.1; AT2G18500.1; AT2G18500.
DR GeneID; 816365; -.
DR Gramene; AT2G18500.1; AT2G18500.1; AT2G18500.
DR KEGG; ath:AT2G18500; -.
DR Araport; AT2G18500; -.
DR TAIR; locus:2046308; AT2G18500.
DR eggNOG; ENOG502QSY1; Eukaryota.
DR HOGENOM; CLU_059469_0_0_1; -.
DR InParanoid; Q9ZU65; -.
DR OMA; KFEWERE; -.
DR OrthoDB; 1169714at2759; -.
DR PhylomeDB; Q9ZU65; -.
DR PRO; PR:Q9ZU65; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZU65; baseline and differential.
DR Genevisible; Q9ZU65; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR038933; Ovate.
DR InterPro; IPR006458; Ovate_C.
DR PANTHER; PTHR33057; PTHR33057; 1.
DR Pfam; PF04844; Ovate; 1.
DR TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR PROSITE; PS51754; OVATE; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..315
FT /note="Transcription repressor OFP7"
FT /id="PRO_0000429676"
FT DOMAIN 230..289
FT /note="OVATE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT REGION 113..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 315 AA; 35543 MW; 7EE92D5D6CE37215 CRC64;
MTKRFKLKIS RILSFKSCRL KDPSSLPFNP VSSSLRRTSP LVNSSADVTT VPQRRRSSFR
LHVLTVFGCG RSSTPLDVDL RNSPVLSPPQ TPTFQWESEG KWHVIAQVTE EEYETPRRKI
YNGGSEKDNR RRLKKKEKSN SRRRGSISSA EEETDRESLL PSSTNLSPEY SSSELPRVTR
RPRQLLKKAV IEEESESSSP PPSPARLSSF VQRLMPCTMA AAVMVEGVAV VKKSEDPYED
FKGSMMEMIV EKKMFEVAEL EQLLSCFLSL NAKRHHRAIV RAFSEIWVAL FSGGSGGGRR
SSSFSSVRLS DYDEC
