OFP8_ARATH
ID OFP8_ARATH Reviewed; 221 AA.
AC Q3E9B4;
DT 09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT 08-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Transcription repressor OFP8;
DE AltName: Full=Ovate family protein 8;
DE Short=AtOFP8;
GN Name=OFP8; OrderedLocusNames=At5g19650; ORFNames=T29J13;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP FUNCTION, TISSUE SPECIFICITY, GENE FAMILY, AND DISRUPTION PHENOTYPE.
RX PubMed=21886836; DOI=10.1371/journal.pone.0023896;
RA Wang S., Chang Y., Guo J., Zeng Q., Ellis B.E., Chen J.G.;
RT "Arabidopsis ovate family proteins, a novel transcriptional repressor
RT family, control multiple aspects of plant growth and development.";
RL PLoS ONE 6:E23896-E23896(2011).
CC -!- FUNCTION: Transcriptional repressor that regulates multiple aspects of
CC plant growth and development through the regulation of BEL1-LIKE (BLH)
CC and KNOX TALE (KNAT) homeodomain transcription factors.
CC {ECO:0000269|PubMed:21886836}.
CC -!- INTERACTION:
CC Q3E9B4; C0SUU6: At1g11510; NbExp=4; IntAct=EBI-1999467, EBI-15191973;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, rosette and cauline leaves,
CC shoots, stems, flower buds and siliques. {ECO:0000269|PubMed:21886836}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21886836}.
CC -!- MISCELLANEOUS: Plants over-expressing OFP8 show flat, thick and cyan
CC leaves, and enhanced apical dormancy. {ECO:0000305|PubMed:21886836}.
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DR EMBL; AF296838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED92734.1; -; Genomic_DNA.
DR RefSeq; NP_197466.1; NM_121970.2.
DR AlphaFoldDB; Q3E9B4; -.
DR BioGRID; 17361; 8.
DR IntAct; Q3E9B4; 8.
DR STRING; 3702.AT5G19650.1; -.
DR PaxDb; Q3E9B4; -.
DR PRIDE; Q3E9B4; -.
DR EnsemblPlants; AT5G19650.1; AT5G19650.1; AT5G19650.
DR GeneID; 832085; -.
DR Gramene; AT5G19650.1; AT5G19650.1; AT5G19650.
DR KEGG; ath:AT5G19650; -.
DR Araport; AT5G19650; -.
DR TAIR; locus:2183209; AT5G19650.
DR eggNOG; ENOG502QSY1; Eukaryota.
DR HOGENOM; CLU_1333580_0_0_1; -.
DR InParanoid; Q3E9B4; -.
DR OMA; YDVVETC; -.
DR OrthoDB; 1232096at2759; -.
DR PhylomeDB; Q3E9B4; -.
DR PRO; PR:Q3E9B4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q3E9B4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR InterPro; IPR038933; Ovate.
DR InterPro; IPR006458; Ovate_C.
DR PANTHER; PTHR33057; PTHR33057; 1.
DR Pfam; PF04844; Ovate; 1.
DR TIGRFAMs; TIGR01568; A_thal_3678; 1.
DR PROSITE; PS51754; OVATE; 1.
PE 1: Evidence at protein level;
KW Nucleus; Reference proteome; Repressor; Transcription;
KW Transcription regulation.
FT CHAIN 1..221
FT /note="Transcription repressor OFP8"
FT /id="PRO_0000429677"
FT DOMAIN 158..217
FT /note="OVATE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01090"
FT REGION 124..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 221 AA; 25466 MW; DC16C728A342B92B CRC64;
MEKRMKLRVS RIVRSSLSSC RPRDLYDVVE TCAVTSKATS SERFFVTKAK TKTPSRPKSH
ASSCPRASPI FPPNPFYEES RSFRDLRKKV KTNRKQRSQF GSDPLFASRF KSTGSWYWSC
SEEEDEGDKE ESEDDDSDTL FSSRSFSSDS SKAESFAVVK KSKDPYEDFR TSMVEMIVER
QIFAPAELQQ LLQCFLSLNS RQHHKVIVQV FLEIYATLFS P
