OGR1_ORYSJ
ID OGR1_ORYSJ Reviewed; 587 AA.
AC B8YEK4; A0A0P0Y8V1; B8YEK3; Q0INZ9; Q2QU89;
DT 24-JUN-2015, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Pentatricopeptide repeat-containing protein OGR1, mitochondrial {ECO:0000305};
DE AltName: Full=Protein OPAQUE AND GROWTH RETARDATION 1 {ECO:0000303|PubMed:19453459};
DE Flags: Precursor;
GN Name=OGR1 {ECO:0000303|PubMed:19453459};
GN OrderedLocusNames=Os12g0270200 {ECO:0000312|EMBL:BAF29566.2},
GN LOC_Os12g17080 {ECO:0000312|EMBL:ABA97375.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBCELLULAR LOCATION, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=19453459; DOI=10.1111/j.1365-313x.2009.03909.x;
RA Kim S.R., Yang J.I., Moon S., Ryu C.H., An K., Kim K.M., Yim J., An G.;
RT "Rice OGR1 encodes a pentatricopeptide repeat-DYW protein and is essential
RT for RNA editing in mitochondria.";
RL Plant J. 59:738-749(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RG The rice full-length cDNA consortium;
RT "Oryza sativa full length cDNA.";
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in multiple sites RNA editing events in
CC mitochondria. Essential for C-to-U RNA editing at seven specific sites
CC of nad2, nad4, cox2, cox3 and ccmC transcripts, all coding for proteins
CC involved in the mitochondrial electron transport chain coupled to ATP
CC generation. Required for normal growth and development.
CC {ECO:0000269|PubMed:19453459}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:19453459}.
CC -!- DISRUPTION PHENOTYPE: Opaque seed endosperm, late germination of seeds
CC and plant retarded growth.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABA97375.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAF29566.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; FJ527826; ACL79585.1; -; Genomic_DNA.
DR EMBL; FJ527827; ACL79586.1; -; Genomic_DNA.
DR EMBL; AL928779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DP000011; ABA97375.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008218; BAF29566.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014968; BAT16644.1; -; Genomic_DNA.
DR EMBL; AK242641; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; XP_015619829.1; XM_015764343.1.
DR RefSeq; XP_015619830.1; XM_015764344.1.
DR RefSeq; XP_015619831.1; XM_015764345.1.
DR RefSeq; XP_015619832.1; XM_015764346.1.
DR RefSeq; XP_015619833.1; XM_015764347.1.
DR AlphaFoldDB; B8YEK4; -.
DR SMR; B8YEK4; -.
DR STRING; 4530.OS12T0270200-01; -.
DR PaxDb; B8YEK4; -.
DR PRIDE; B8YEK4; -.
DR EnsemblPlants; Os12t0270200-01; Os12t0270200-01; Os12g0270200.
DR GeneID; 4351952; -.
DR Gramene; Os12t0270200-01; Os12t0270200-01; Os12g0270200.
DR KEGG; osa:4351952; -.
DR eggNOG; KOG4197; Eukaryota.
DR HOGENOM; CLU_002706_37_1_1; -.
DR OMA; NMKHYGT; -.
DR OrthoDB; 1344243at2759; -.
DR Proteomes; UP000000763; Chromosome 12.
DR Proteomes; UP000059680; Chromosome 12.
DR GO; GO:0005739; C:mitochondrion; IDA:UniProtKB.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0080156; P:mitochondrial mRNA modification; IMP:UniProtKB.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR032867; DYW_dom.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR Pfam; PF14432; DYW_deaminase; 1.
DR Pfam; PF01535; PPR; 4.
DR Pfam; PF12854; PPR_1; 1.
DR TIGRFAMs; TIGR00756; PPR; 4.
DR PROSITE; PS51375; PPR; 7.
PE 2: Evidence at transcript level;
KW Mitochondrion; mRNA processing; Reference proteome; Repeat;
KW Transit peptide.
FT TRANSIT 1..30
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 31..587
FT /note="Pentatricopeptide repeat-containing protein OGR1,
FT mitochondrial"
FT /evidence="ECO:0000255"
FT /id="PRO_0000433269"
FT REPEAT 145..179
FT /note="PPR 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 200..203
FT /note="PPR 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 217..251
FT /note="PPR 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 252..286
FT /note="PPR 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 287..315
FT /note="PPR 5"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 319..349
FT /note="PPR 6"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 351..381
FT /note="PPR 7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REPEAT 383..417
FT /note="PPR 8"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00708"
FT REGION 386..461
FT /note="Type E motif"
FT /evidence="ECO:0000250|UniProtKB:Q7Y211"
FT REGION 462..492
FT /note="Type E(+) motif"
FT /evidence="ECO:0000250|UniProtKB:Q7Y211"
FT REGION 493..587
FT /note="Type DYW motif"
FT /evidence="ECO:0000250|UniProtKB:Q7Y211"
FT CONFLICT 1..4
FT /note="MSVS -> MSVSAA (in Ref. 1; ACL79585)"
FT /evidence="ECO:0000305"
FT CONFLICT 224
FT /note="A -> V (in Ref. 1; ACL79585)"
FT /evidence="ECO:0000305"
FT CONFLICT 246
FT /note="R -> K (in Ref. 1; ACL79585)"
FT /evidence="ECO:0000305"
FT CONFLICT 284
FT /note="Q -> R (in Ref. 1; ACL79585)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 587 AA; 64618 MW; 2B796AB4F709F591 CRC64;
MSVSAAARHL ESLLPRLASL RHYLQFHARL LTSGHLGAHP GLRARFLDRL ALSPHPAALP
HALLLLRSLP TPATNDLNAA LRGLAASPHP ARSLLLLAGR LLPALLPRPD ALSLSFALKA
SARCSDAHTT VQLHALVLRL GVAADVRLLT TLLDSYAKCG DLASARKVFD EMTVRDVATW
NSLLAGLAQG TEPNLALALF HRLANSFQEL PSREEPNEVT IVAALSACAQ IGLLKDGMYV
HEFAKRFGLD RNVRVCNSLI DMYSKCGSLS RALDVFHSIK PEDQTLVSYN AAIQAHSMHG
HGGDALRLFD EMPTRIEPDG VTYLAVLCGC NHSGLVDDGL RVFNSMRVAP NMKHYGTIVD
LLGRAGRLTE AYDTVISMPF PADIVLWQTL LGAAKMHGVV ELAELAANKL AELGSNVDGD
YVLLSNVYAS KARWMDVGRV RDTMRSNDVR KVPGFSYTEI DGVMHKFING DKEHPRWQEI
YRALEDIVSR ISELGYEPET SNVLHDIGEE EKQYALCYHS EKLAIAFGLI ATPPGETLRV
IKNLRICGDC HVVAKLISKA YGRVIVIRDR ARFHRFEDGQ CSCRDYW
