OHK3_ORYSI
ID OHK3_ORYSI Reviewed; 1023 AA.
AC A2WYI4; Q2Q1D4;
DT 16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Probable histidine kinase 3 {ECO:0000305};
DE Short=OsHK3 {ECO:0000305};
DE EC=2.7.13.3 {ECO:0000305};
GN Name=HK3 {ECO:0000305}; Synonyms=OHK2;
GN ORFNames=OsI_04985 {ECO:0000312|EMBL:EAY77030.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. IR64;
RA Kumar M., Bansal A., Singla-Pareek S.L., Sopory S.K., Pareek A.;
RT "A hybrid type histidine kinase OsHK is inducible by multiple stresses in
RT Oryza sativa L. cv. IR64.";
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Cytokinin receptor related to bacterial two-component
CC regulators. Functions as a histidine kinase and transmits the stress
CC signal to a downstream MAPK cascade. {ECO:0000250|UniProtKB:A1A698}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000305};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- DOMAIN: Histidine-containing phosphotransfer domain (HPt) contains an
CC active histidine that mediates the phosphotransfer. {ECO:0000305}.
CC -!- PTM: Activation probably requires a transfer of a phosphate group
CC between a His in the transmitter domain and an Asp of the receiver
CC domain. {ECO:0000305}.
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DR EMBL; DQ248962; ABB76249.1; -; mRNA.
DR EMBL; CM000126; EAY77030.1; -; Genomic_DNA.
DR AlphaFoldDB; A2WYI4; -.
DR SMR; A2WYI4; -.
DR STRING; 39946.A2WYI4; -.
DR EnsemblPlants; BGIOSGA000228-TA; BGIOSGA000228-PA; BGIOSGA000228.
DR Gramene; BGIOSGA000228-TA; BGIOSGA000228-PA; BGIOSGA000228.
DR HOGENOM; CLU_000445_16_2_1; -.
DR OMA; TQQDYVK; -.
DR Proteomes; UP000007015; Chromosome 1.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0043424; F:protein histidine kinase binding; IEA:EnsemblPlants.
DR GO; GO:0071215; P:cellular response to abscisic acid stimulus; IEA:EnsemblPlants.
DR GO; GO:0070417; P:cellular response to cold; IEA:EnsemblPlants.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IEA:EnsemblPlants.
DR GO; GO:0071329; P:cellular response to sucrose stimulus; IEA:EnsemblPlants.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:EnsemblPlants.
DR GO; GO:0010150; P:leaf senescence; IEA:EnsemblPlants.
DR GO; GO:0034757; P:negative regulation of iron ion transport; IEA:EnsemblPlants.
DR GO; GO:0010087; P:phloem or xylem histogenesis; IEA:EnsemblPlants.
DR GO; GO:0010271; P:regulation of chlorophyll catabolic process; IEA:EnsemblPlants.
DR GO; GO:0009909; P:regulation of flower development; IEA:EnsemblPlants.
DR GO; GO:0048509; P:regulation of meristem development; IEA:EnsemblPlants.
DR GO; GO:0010029; P:regulation of seed germination; IEA:EnsemblPlants.
DR GO; GO:0009651; P:response to salt stress; IEA:EnsemblPlants.
DR GO; GO:0009414; P:response to water deprivation; IEA:EnsemblPlants.
DR GO; GO:0080117; P:secondary growth; IEA:EnsemblPlants.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 3.30.450.350; -; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF47384; SSF47384; 1.
DR SUPFAM; SSF52172; SSF52172; 2.
DR SUPFAM; SSF55874; SSF55874; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 2: Evidence at transcript level;
KW Cell membrane; Cytokinin signaling pathway; Kinase; Membrane;
KW Phosphoprotein; Reference proteome; Repeat; Transferase; Transmembrane;
KW Transmembrane helix; Two-component regulatory system.
FT CHAIN 1..1023
FT /note="Probable histidine kinase 3"
FT /id="PRO_0000433808"
FT TOPO_DOM 1..80
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 102..387
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 409..1023
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT DOMAIN 151..352
FT /note="CHASE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00049"
FT DOMAIN 445..715
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT DOMAIN 732..854
FT /note="Response regulatory 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 880..1016
FT /note="Response regulatory 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT REGION 812..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 814..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 448
FT /note="Phosphohistidine; by autocatalysis"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT MOD_RES 783
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 930
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT CONFLICT 188
FT /note="R -> Q (in Ref. 1; ABB76249)"
FT /evidence="ECO:0000305"
FT CONFLICT 555
FT /note="I -> V (in Ref. 1; ABB76249)"
FT /evidence="ECO:0000305"
FT CONFLICT 563
FT /note="V -> I (in Ref. 1; ABB76249)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1023 AA; 113272 MW; F4DE16A44DC6447E CRC64;
MDEMSCGGGG GGARWKRARV AGMGEGKAGG GGGAAFLGLE RVGMVVRMLP VPEKVSARAR
VVRGSLVAHF RGWRVVRETW WWVLLLWILA GSLGSFYLFL FMNAQSLDKR RDSLASMCDE
RARMLQDQFN VSMNHLQALA ILVSTFHHSK TPSAIDQMTF ARYAERTAFE RPLTSGVAYA
VRVTHGEREQ FERQQGWAIK KMYSSSNKKQ SSPGPGPGDA AVAEIREPAE EYAPVIFAQD
AYKHVISFDM LSGNEDRDNI LRARKSGKGV LTAPFKLLNN RLGVILTYTV YKYELPAYAR
PHERIQAAIG YLGGIFDIQA LVEKLLKQLA SQESIMVNVY DTTNESPISM YGDDTGSGMC
HVSVLNFGDP SRKHEMHCRF EKKPPWPWLA ITSSFGTLVI ALLTGHIFQA TVHRIAKVED
DFHKMSELKK RAEDADVAKS QFLATVSHEI RTPMNGVLGM LQMLMDTDLD TTQQDYVRTA
QASGKALVSL INEVLDQAKI ESGKLELETV PFDLRTVCDD ILSLFCGKAQ EKGLELAVYV
SDQVPQILIG DPGRIRQIIT NLVGNSIKFT ERGHIYLTVH VVEEVMSCLE VETGIQNTNT
LSGYPVANRR RSWESIRLFN RELHSSEKSF APIASDSISL VISVEDTGVG IPFEAQSRVF
TPFMQVGPSI ARIHGGTGIG LSISKCLVGL MKGEIGFASK PHVGSTFTFT AVLMRAHCKG
NDIKSSEFKG INALVVDHRP VRAKVTKYHL QRLGVKTELT AELNQFISKL NSGSLTAKLV
LIDKETWLKE SHCTPLLVNK LRNNDKPDSP KLFLLGSSAS SPKGGSDTSR EHNLNVIMKP
LRASMLQVSL RRALGGVDKV HCRNGVVGNS TLGSLLHKKQ IIVVDDNIVN LKVAAGALKK
YGAEVTCADS GKKAITLLKP PHNFDACFMD IQMPEMDGFE ATRRIRVMER DLNERIERGE
APPECASIQR WRTPILAMTA DVIQATHEEC LKSEMDGYVS KPFEGEQLYS EVARFFQNHD
QVE
