OHK5_ORYSJ
ID OHK5_ORYSJ Reviewed; 1187 AA.
AC A1A697; Q0IY65; Q14U60; Q7G3E3; Q8S6P5;
DT 16-SEP-2015, integrated into UniProtKB/Swiss-Prot.
DT 13-OCT-2009, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Probable histidine kinase 5 {ECO:0000305};
DE Short=OsHK5 {ECO:0000303|PubMed:22642989};
DE EC=2.7.13.3 {ECO:0000305};
DE AltName: Full=OsCRL3 {ECO:0000305};
GN Name=HK5 {ECO:0000303|PubMed:17284581};
GN Synonyms=OHK3 {ECO:0000303|PubMed:16919402};
GN OrderedLocusNames=Os10g0362300 {ECO:0000312|EMBL:BAF26350.2},
GN LOC_Os10g21810 {ECO:0000312|EMBL:AAP53311.2};
GN ORFNames=OsJ_31230 {ECO:0000312|EMBL:EEE50822.1},
GN OSJNBa0073L01.1 {ECO:0000312|EMBL:AAM18726.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16919402; DOI=10.1016/j.gene.2006.06.020;
RA Ito Y., Kurata N.;
RT "Identification and characterization of cytokinin-signalling gene families
RT in rice.";
RL Gene 382:57-65(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12791992; DOI=10.1126/science.1083523;
RA Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT "In-depth view of structure, activity, and evolution of rice chromosome
RT 10.";
RL Science 300:1566-1569(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP DISRUPTION PHENOTYPE.
RX PubMed=16891544; DOI=10.1104/pp.106.086371;
RA Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA Singla-Pareek S.L.;
RT "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT component signaling machinery with Arabidopsis.";
RL Plant Physiol. 142:380-397(2006).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17284581; DOI=10.1104/pp.106.093666;
RA Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT "Nomenclature for two-component signaling elements of rice.";
RL Plant Physiol. 143:555-557(2007).
RN [9]
RP TISSUE SPECIFICITY.
RX PubMed=22642989; DOI=10.1093/pcp/pcs079;
RA Choi J., Lee J., Kim K., Cho M., Ryu H., An G., Hwang I.;
RT "Functional identification of OsHk6 as a homotypic cytokinin receptor in
RT rice with preferential affinity for iP.";
RL Plant Cell Physiol. 53:1334-1343(2012).
CC -!- FUNCTION: Cytokinin receptor related to bacterial two-component
CC regulators. Functions as a histidine kinase and transmits the stress
CC signal to a downstream MAPK cascade. {ECO:0000250|UniProtKB:A1A698}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000305};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Highly expressed in young leaves and at lower
CC levels in roots, mature leaves, stems and spikelets.
CC {ECO:0000269|PubMed:22642989}.
CC -!- DOMAIN: Histidine-containing phosphotransfer domain (HPt) contains an
CC active histidine that mediates the phosphotransfer. {ECO:0000305}.
CC -!- PTM: Activation probably requires a transfer of a phosphate group
CC between a His in the transmitter domain and an Asp of the receiver
CC domain. {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Extreme dwarf, low tillering and no heading
CC phenotypes. {ECO:0000269|PubMed:16891544}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM18726.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAP53311.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAE97709.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAF26350.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=EEE50822.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB246778; BAE97709.1; ALT_INIT; mRNA.
DR EMBL; BR000245; FAA00249.1; -; Genomic_DNA.
DR EMBL; AC092548; AAM18726.1; ALT_SEQ; Genomic_DNA.
DR EMBL; DP000086; AAP53311.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP008216; BAF26350.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000147; EEE50822.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_015614148.1; XM_015758662.1.
DR AlphaFoldDB; A1A697; -.
DR SMR; A1A697; -.
DR STRING; 4530.OS10T0362300-01; -.
DR PaxDb; A1A697; -.
DR PRIDE; A1A697; -.
DR EnsemblPlants; Os10t0362300-03; Os10t0362300-03; Os10g0362300.
DR GeneID; 4348447; -.
DR Gramene; Os10t0362300-03; Os10t0362300-03; Os10g0362300.
DR KEGG; osa:4348447; -.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_449323_0_0_1; -.
DR OrthoDB; 51398at2759; -.
DR Proteomes; UP000000763; Chromosome 10.
DR Proteomes; UP000007752; Chromosome 10.
DR Proteomes; UP000059680; Chromosome 10.
DR ExpressionAtlas; A1A697; baseline and differential.
DR Genevisible; A1A697; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 3.30.450.350; -; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF47384; SSF47384; 1.
DR SUPFAM; SSF52172; SSF52172; 2.
DR SUPFAM; SSF55874; SSF55874; 1.
DR PROSITE; PS50839; CHASE; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 2.
PE 2: Evidence at transcript level;
KW Cell membrane; Cytokinin signaling pathway; Kinase; Membrane;
KW Phosphoprotein; Reference proteome; Repeat; Transferase; Transmembrane;
KW Transmembrane helix; Two-component regulatory system.
FT CHAIN 1..1187
FT /note="Probable histidine kinase 5"
FT /id="PRO_0000433810"
FT TOPO_DOM 1..175
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 197..226
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 248..531
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 532..552
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 553..1187
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT DOMAIN 295..519
FT /note="CHASE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00049"
FT DOMAIN 587..862
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT DOMAIN 886..1017
FT /note="Response regulatory 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT DOMAIN 1041..1178
FT /note="Response regulatory 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 590
FT /note="Phosphohistidine; by autocatalysis"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT MOD_RES 942
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT MOD_RES 1091
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1187 AA; 130509 MW; 19790C75B5A73CF8 CRC64;
MSRVGECGGG GGCGARRGKA AHAGAGAVAG FLGCLLLVWA MGGCGRGCGG GGGEGVRDRV
EEVAAQFNLS MSKLQALASL LSSPERECIC KSGTINDDNP AHSMPDMSNC RLKNKPSGGN
QNRLDNVIIQ DCCANEDNYD KNNHENNLLQ NAMQQDIGSP TTLWNQNNAL SFNHGMIFSL
SASLGIVVIL VVITIFKRGK QANELCQHEK LLQTPSVKIS RKWSKRALLL GVLVGLCSSV
WIFSSMHADV VARRIENLEN MCDERARMLQ DQFNVSMNHV HALAILVSTF HHGKNPSAID
QKTFEDFTAR TTFERPLMSG VAYALKVLHS ERELFEQKLG WKIKKMETED QSLVHDYNPE
KLQPSPVQDE YAPVIFSQET VKHIISVDMM SGKEDRDNIL RSRATGKGAL TAPFPLLKSN
HLGVVLTFTV YKYDLPPDAT PEERIEATLG YLGASFDVPS LVERLLEQLA SKQKIVVRLY
DITNHTYPTK MYDSDVIASD DLHISNIDFG DPTRKHVMHC RFKHAPSLPW SAIMISSAVA
IIVLLVGYII YATLNSLEEA EDNYTTMRDL KGRAEAADVA KSQFLATVSH EIRTPMNGVL
GMLQMLMDTE LDTTQRDFVV TAQESGKSLI NLINEVLDLA KIESGKIELE AVRFDVRDIL
DNVVSLFSEK SWAKGIELAV LVSDQVPDVL IGDPWRFRQI ITNLVGNSMK FTEQGHIFIR
VHLIEEVKRK MEALDDTSPE NIEVTANSKN TMPYNTLSGL EVANNRKTLE SFRMFKDSSD
AIDSVNLLVT VEDTGIGITK DAQTRIFTPF MQADGSTSRT YGGTGIGLSI TKRLVELMGG
EIGFVSKPGV SSTFSFTAIF KENRKDPGDI KRYCPEPTPP DFQGMRALVV DGRCARAEVT
MYHLRRLGIQ CDLAATSESA LSALLESCNS SVKSSLNMVL VDKEAWGEDS GLAFFRCLID
LRLKGTLKSW QTMPKFFLLA GSITPADSDC LRLAGYSNSI RKPLRLSTVA ACLSKALGVG
LTGRRSRDNS LVLRSVLTGK NILVVDDNAV NRIVAAGALK KYGAIVTCVD SGKEAISRLQ
PPHKFDACFM DVQMPEMDGF EATRLVRSVE SKINDTIQAG EVSSEIYGNK AHWHVPILAM
TADVIQATFE GCMECGMDGY VAKPFEEQQL YSAVAHFLEA DATDPLT
