OHP1_ORYSJ
ID OHP1_ORYSJ Reviewed; 147 AA.
AC Q6VAK3; A0A0P0XJB0; Q6PT60;
DT 22-JUL-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Histidine-containing phosphotransfer protein 1 {ECO:0000305};
DE AltName: Full=OsAHP1 {ECO:0000303|PubMed:24578505};
DE AltName: Full=OsHP1 {ECO:0000312|EMBL:AAV31128.1};
DE AltName: Full=OsHP2 {ECO:0000312|EMBL:AAQ24030.1};
DE AltName: Full=OsHPt1 {ECO:0000312|EMBL:AAS90601.1};
DE AltName: Full=OsHpt2 {ECO:0000303|PubMed:16891544};
GN Name=AHP1 {ECO:0000303|PubMed:17284581};
GN Synonyms=HP2 {ECO:0000312|EMBL:AAQ24030.1},
GN HPT1 {ECO:0000312|EMBL:AAS90601.1}, OHP1 {ECO:0000303|PubMed:16919402};
GN OrderedLocusNames=Os08g0557700 {ECO:0000312|EMBL:BAF24401.1},
GN LOC_Os08g44350 {ECO:0000305};
GN ORFNames=OJ1150_A11.26 {ECO:0000312|EMBL:BAD09087.1},
GN OsJ_28261 {ECO:0000312|EMBL:EEE69138.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Nipponbare;
RX PubMed=16919402; DOI=10.1016/j.gene.2006.06.020;
RA Ito Y., Kurata N.;
RT "Identification and characterization of cytokinin-signalling gene families
RT in rice.";
RL Gene 382:57-65(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Gu Z.M., Zhang H.S., Huang J.;
RT "Characterization of genes for two-component phosphorelay mediators with a
RT single HPt domain in Oryza sativa.";
RL Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Zhonghua 11;
RA Qu L., Gu H.;
RT "Characterization of two downstream proteins in a possible two-component
RT system in the early responses of rice to infection by a fungal pathogen.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Dongjin;
RA Yun S.J., Park M.-R., Park M.-H., Lim J.-H.;
RT "Regulation of rice histidine-containing phosphotransfer protein gene
RT expression by nutrient availability.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [7]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [9]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [10]
RP DISRUPTION PHENOTYPE.
RX PubMed=16891544; DOI=10.1104/pp.106.086371;
RA Pareek A., Singh A., Kumar M., Kushwaha H.R., Lynn A.M.,
RA Singla-Pareek S.L.;
RT "Whole-genome analysis of Oryza sativa reveals similar architecture of two-
RT component signaling machinery with Arabidopsis.";
RL Plant Physiol. 142:380-397(2006).
RN [11]
RP TISSUE SPECIFICITY.
RX PubMed=17408920; DOI=10.1016/j.ygeno.2007.02.001;
RA Du L., Jiao F., Chu J., Jin G., Chen M., Wu P.;
RT "The two-component signal system in rice (Oryza sativa L.): a genome-wide
RT study of cytokinin signal perception and transduction.";
RL Genomics 89:697-707(2007).
RN [12]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17284581; DOI=10.1104/pp.106.093666;
RA Schaller G.E., Doi K., Hwang I., Kieber J.J., Khurana J.P., Kurata N.,
RA Mizuno T., Pareek A., Shiu S.H., Wu P., Yip W.K.;
RT "Nomenclature for two-component signaling elements of rice.";
RL Plant Physiol. 143:555-557(2007).
RN [13]
RP SUBCELLULAR LOCATION.
RX PubMed=22383541; DOI=10.1104/pp.111.192765;
RA Tsai Y.C., Weir N.R., Hill K., Zhang W., Kim H.J., Shiu S.H.,
RA Schaller G.E., Kieber J.J.;
RT "Characterization of genes involved in cytokinin signaling and metabolism
RT from rice.";
RL Plant Physiol. 158:1666-1684(2012).
RN [14]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=24578505; DOI=10.1104/pp.113.232629;
RA Sun L., Zhang Q., Wu J., Zhang L., Jiao X., Zhang S., Zhang Z., Sun D.,
RA Lu T., Sun Y.;
RT "Two rice authentic histidine phosphotransfer proteins, OsAHP1 and OsAHP2,
RT mediate cytokinin signaling and stress responses in rice.";
RL Plant Physiol. 165:335-345(2014).
CC -!- FUNCTION: Functions as two-component phosphorelay mediators between
CC cytokinin sensor histidine kinases and response regulators (B-type
CC ARRs). Plays an important role in propagating cytokinin signal
CC transduction through the multistep His-to-Asp phosphorelay (By
CC similarity). Functions as positive regulator of the cytokinin signaling
CC pathway. May play a regulatory role in salt and drought tolerance
CC during plant development (PubMed:24578505).
CC {ECO:0000250|UniProtKB:Q8L9T7, ECO:0000269|PubMed:24578505}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol {ECO:0000269|PubMed:22383541,
CC ECO:0000269|PubMed:24578505}. Nucleus {ECO:0000269|PubMed:22383541,
CC ECO:0000269|PubMed:24578505}.
CC -!- TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:16919402,
CC ECO:0000269|PubMed:17408920}.
CC -!- DOMAIN: Histidine-containing phosphotransfer domain (HPt) contains an
CC active histidine that mediates the phosphotransfer. {ECO:0000305}.
CC -!- PTM: Two-component system major event consists of a His-to-Asp
CC phosphorelay between a sensor histidine kinase (HK) and a response
CC regulator (RR). In plants, the His-to-Asp phosphorelay involves an
CC additional intermediate named Histidine-containing phosphotransfer
CC protein (HPt). This multistep phosphorelay consists of a His-Asp-His-
CC Asp sequential transfer of a phosphate group between first an His and
CC an Asp of the HK protein, followed by the transfer to a conserved His
CC of the HPt protein and finally the transfer to an Asp in the receiver
CC domain of the RR protein. {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Dwarf, wide leaf and small grain phenotypes.
CC {ECO:0000269|PubMed:16891544}.
CC -!- MISCELLANEOUS: Plant silencing simultaneously OHP1 and OHP2 exhibit
CC phenotypes for a deficiency in cytokinin signaling, including dwarfism
CC with reduced internode lengths, enhanced lateral root growth, early
CC leaf senescence, and reduced tiller numbers and fertility.
CC {ECO:0000269|PubMed:24578505}.
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DR EMBL; BR000248; FAA00252.1; -; Genomic_DNA.
DR EMBL; AY345242; AAQ24030.1; -; mRNA.
DR EMBL; AY581257; AAS90601.1; -; mRNA.
DR EMBL; AY569613; AAV31128.1; -; mRNA.
DR EMBL; AP003928; BAD09087.1; -; Genomic_DNA.
DR EMBL; AP008214; BAF24401.1; -; Genomic_DNA.
DR EMBL; AP014964; BAT06668.1; -; Genomic_DNA.
DR EMBL; CM000145; EEE69138.1; -; Genomic_DNA.
DR EMBL; AK061111; BAG87734.1; -; mRNA.
DR RefSeq; XP_015648297.1; XM_015792811.1.
DR AlphaFoldDB; Q6VAK3; -.
DR SMR; Q6VAK3; -.
DR STRING; 4530.OS08T0557700-01; -.
DR PaxDb; Q6VAK3; -.
DR PRIDE; Q6VAK3; -.
DR EnsemblPlants; Os08t0557700-01; Os08t0557700-01; Os08g0557700.
DR GeneID; 4346300; -.
DR Gramene; Os08t0557700-01; Os08t0557700-01; Os08g0557700.
DR KEGG; osa:4346300; -.
DR eggNOG; KOG4747; Eukaryota.
DR HOGENOM; CLU_111777_3_0_1; -.
DR InParanoid; Q6VAK3; -.
DR OMA; SITREYC; -.
DR OrthoDB; 1488145at2759; -.
DR Proteomes; UP000000763; Chromosome 8.
DR Proteomes; UP000007752; Chromosome 8.
DR Proteomes; UP000059680; Chromosome 8.
DR Genevisible; Q6VAK3; OS.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; IDA:UniProtKB.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0009927; F:histidine phosphotransfer kinase activity; IBA:GO_Central.
DR GO; GO:0043424; F:protein histidine kinase binding; IBA:GO_Central.
DR GO; GO:0009736; P:cytokinin-activated signaling pathway; IBA:GO_Central.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IBA:GO_Central.
DR GO; GO:0016310; P:phosphorylation; IBA:GO_Central.
DR GO; GO:0080038; P:positive regulation of cytokinin-activated signaling pathway; IMP:UniProtKB.
DR CDD; cd00088; HPT; 1.
DR Gene3D; 1.20.120.160; -; 1.
DR InterPro; IPR045871; AHP1-5/YPD1.
DR InterPro; IPR036641; HPT_dom_sf.
DR InterPro; IPR008207; Sig_transdc_His_kin_Hpt_dom.
DR PANTHER; PTHR28242; PTHR28242; 1.
DR Pfam; PF01627; Hpt; 1.
DR SUPFAM; SSF47226; SSF47226; 1.
DR PROSITE; PS50894; HPT; 1.
PE 2: Evidence at transcript level;
KW Cytokinin signaling pathway; Cytoplasm; Nucleus; Phosphoprotein;
KW Reference proteome; Sensory transduction; Two-component regulatory system.
FT CHAIN 1..147
FT /note="Histidine-containing phosphotransfer protein 1"
FT /id="PRO_0000433565"
FT DOMAIN 38..133
FT /note="HPt"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00110"
FT MOD_RES 79
FT /note="Phosphohistidine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00110"
FT CONFLICT 8
FT /note="S -> G (in Ref. 3; AAS90601)"
FT /evidence="ECO:0000305"
FT CONFLICT 80
FT /note="Q -> R (in Ref. 3; AAS90601)"
FT /evidence="ECO:0000305"
FT CONFLICT 107
FT /note="R -> K (in Ref. 3; AAS90601)"
FT /evidence="ECO:0000305"
FT CONFLICT 143
FT /note="C -> W (in Ref. 3; AAS90601)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 147 AA; 16792 MW; 47C148AE0212B024 CRC64;
MAAAALTSQL NALVNNMFAM GLLDDQFQQL QMLQDSTAPD FVSEVVTLFC DDGERIICEL
SRQLEKPNVD FDRVDSYVHQ LKGSSASVGA QKVKNTCIQF REFCQQRSRD GCLKTLDLVR
TEFYDLRNKF QAMLQLEQQI QACYPKH
