ID   ART10_ASHGO             Reviewed;         430 AA.
AC   Q757F4;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Arrestin-related trafficking adapter 10;
GN   Name=ART10; OrderedLocusNames=AER059C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: May regulate endocytosis by recruiting RSP5 ubiquitin ligase
CC       activity to specific plasma membrane proteins in response to
CC       extracellular stimuli. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ART10 family. {ECO:0000305}.
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DR   EMBL; AE016818; AAS52743.1; -; Genomic_DNA.
DR   RefSeq; NP_984919.1; NM_210273.1.
DR   AlphaFoldDB; Q757F4; -.
DR   STRING; 33169.AAS52743; -.
DR   EnsemblFungi; AAS52743; AAS52743; AGOS_AER059C.
DR   GeneID; 4621122; -.
DR   KEGG; ago:AGOS_AER059C; -.
DR   eggNOG; ENOG502QWIY; Eukaryota.
DR   HOGENOM; CLU_540776_0_0_1; -.
DR   InParanoid; Q757F4; -.
DR   OMA; FKTCTIK; -.
DR   Proteomes; UP000000591; Chromosome V.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0030674; F:protein-macromolecule adaptor activity; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR   GO; GO:0070086; P:ubiquitin-dependent endocytosis; IBA:GO_Central.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
PE   3: Inferred from homology;
KW   Cytoplasm; Endocytosis; Reference proteome.
FT   CHAIN           1..430
FT                   /note="Arrestin-related trafficking adapter 10"
FT                   /id="PRO_0000402191"
FT   REGION          55..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   430 AA;  48188 MW;  6C045ACF97C77AE2 CRC64;
     MTTKITLKLN PPHNGRYYTE DDIISGSVVL KLAKATAVKQ LRVILKGTSQ TMTLAEADRH
     SSRLPQDPQT QYTKEKSTHI LFHQGVQLLP PTGVEDSIKL GQDTYKYGFE FRLAGGPKCV
     SGHQATSHSF LEDKAHEHYG EQLPPSFNDR HEGGGVTTEE LFFYNLGKVR YTVRAEADVA
     TGNKWAPKSP LHDTMVISFL PLQCQAYVEN ACTSAGSDDT LVNYTALPRT YRAAADVVLS
     DGLSVTPEVR SNALAYVHRL DYLFRESSGK FGNIFMVFSG DPTKHSVKLT RLVLSLHEKV
     SFTANGHTNK NLSQLKLMDT PLDDELQLRD LHILEDGSRE GKLNLGDHPV LSRLRFNEED
     YIHRGNTLFS FTTCNIKREY YFQLDLHWKV DATAVRSEII VDPVTVYAES APPAFEGLPP
     YPEKPPKYEA