ID   ART10_VANPO             Reviewed;         550 AA.
AC   A7TGF3;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Arrestin-related trafficking adapter 10;
GN   Name=ART10; ORFNames=Kpol_1055p80;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: May regulate endocytosis by recruiting RSP5 ubiquitin ligase
CC       activity to specific plasma membrane proteins in response to
CC       extracellular stimuli. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ART10 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS480386; EDO18723.1; -; Genomic_DNA.
DR   RefSeq; XP_001646581.1; XM_001646531.1.
DR   AlphaFoldDB; A7TGF3; -.
DR   STRING; 436907.A7TGF3; -.
DR   EnsemblFungi; EDO18723; EDO18723; Kpol_1055p80.
DR   GeneID; 5547033; -.
DR   KEGG; vpo:Kpol_1055p80; -.
DR   eggNOG; ENOG502QWIY; Eukaryota.
DR   HOGENOM; CLU_540776_0_0_1; -.
DR   InParanoid; A7TGF3; -.
DR   OMA; FKTCTIK; -.
DR   OrthoDB; 1292751at2759; -.
DR   PhylomeDB; A7TGF3; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR011021; Arrestin-like_N.
DR   Pfam; PF00339; Arrestin_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endocytosis; Reference proteome.
FT   CHAIN           1..550
FT                   /note="Arrestin-related trafficking adapter 10"
FT                   /id="PRO_0000402199"
FT   REGION          275..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   550 AA;  64397 MW;  AEB3A9CB9F198EBC CRC64;
     MSKINLTLDP PYNGEYYTGT EQISGHVSIQ IEKPISIKSI SIKLKGFIQT LTKIDSDQMF
     NNNSAMSPIQ DNRAIHNIVE KSHRLFPPDN VWNALEGSHK PFKVKPGLYE YNFEFDKMPK
     RPECLARHKR DTDSFVKRNE TRMPPSFNNN WKDMSRVDNI ELYYYTLGKV IYIVQVEIEL
     GKALAWYKPF NKFLHETLNI DYIPDAKDLI YVEDPEDYIA RNSRVESDEQ LIESIQNSLA
     LNNNNNNTNN NIDNNNNRIK NKNININDGK IDNDGISTNS NTESNQVLTG DIGSNNTLMG
     RNNNMSVNSE NRLNEHVIYK SSFSVQLPDE SSVMWLEVRS RGLRHTYRRD YLFRQGSNKF
     DNIYLVLEGD IEEMFKMKIN PRKIQLNLLE QTVYVAQGIA NENVSSLRLV EALKICDDDD
     EFGRIFQFNP IQVPSNLHHR HHNNDAHNKK YEVELCLKDH SILKRIRFNK EDYVHRGNRL
     YSFKTCTIKR LFKFQLLIDW QINDKIRTTE NIIDRTQIFC QVREKVNVVD TLPQYVEPPQ
     YTETRHTTTP