ART10_YEAS2
ID ART10_YEAS2 Reviewed; 518 AA.
AC C7GXJ6;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 13-OCT-2009, sequence version 1.
DT 25-MAY-2022, entry version 25.
DE RecName: Full=Arrestin-related trafficking adapter 10;
GN Name=ART10; ORFNames=C1Q_05259;
OS Saccharomyces cerevisiae (strain JAY291) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=574961;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAY291;
RX PubMed=19812109; DOI=10.1101/gr.091777.109;
RA Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., Netto O.V.C.,
RA Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., Noronha M.F.,
RA Dominska M., Andrietta M.G.S., Andrietta S.R., Cunha A.F., Gomes L.H.,
RA Tavares F.C.A., Alcarde A.R., Dietrich F.S., McCusker J.H., Petes T.D.,
RA Pereira G.A.G.;
RT "Genome structure of a Saccharomyces cerevisiae strain widely used in
RT bioethanol production.";
RL Genome Res. 19:2258-2270(2009).
CC -!- FUNCTION: May regulate endocytosis by recruiting RSP5 ubiquitin ligase
CC activity to specific plasma membrane proteins in response to
CC extracellular stimuli. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with RSP5. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- PTM: Ubiquitinated by RSP5. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ART10 family. {ECO:0000305}.
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DR EMBL; ACFL01000434; EEU04461.1; -; Genomic_DNA.
DR AlphaFoldDB; C7GXJ6; -.
DR Proteomes; UP000008073; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.640; -; 1.
DR InterPro; IPR014752; Arrestin-like_C.
PE 3: Inferred from homology;
KW Cytoplasm; Endocytosis; Isopeptide bond; Ubl conjugation.
FT CHAIN 1..518
FT /note="Arrestin-related trafficking adapter 10"
FT /id="PRO_0000402195"
FT CROSSLNK 118
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in ubiquitin)"
FT /evidence="ECO:0000250|UniProtKB:P18634"
SQ SEQUENCE 518 AA; 59765 MW; 5F176139FCDAF0DE CRC64;
MAPKISISLN PPYNGEFYSS NDQMSGIVSL QLTKALSIRK ISVILKGFSE TLTKIDQEYM
FQQNGMMMPG QDNKSFHTLM KFEQRVFPPD NVWNALDGSS KPFKVKPGSY NYSFQFDKFP
RKPECLKNHT AKTVAFVTRN NARLPPTFNS HWQEFNKIDN LDLYFYSFGK VIYMVQVQIE
LGKSSSWFKP FHKLIREIET FEFIPEPKDL IVEPDEDDNE ELNAFSNNSR GNSLVTNNEF
FNSSNLKVPS KDVKVVNGVG YIKSDRNFSQ ANSILIENGD IRSRPVSSVT STRQSTRLVN
GMKVFPSTYK MGLPDGESNM RIEVRSRDLK QIYRKDYLFR SGSQNFDKVY VVMEGNIASL
SKMQITPLKL QLNLLETTTY LSQGIANGNY SSLKLIEIDL NQLKSNKPLL DLNEIRENFD
GSMFECELRL KDHPILRKLV FNEEDYRHRG NRLYSFKTCT IKRIFSLQLL IEWGINGIRK
QSEVNIDPVQ IFCQVREHVE AEALPRYVPP PTYTEMAS