OL477_MOUSE
ID OL477_MOUSE Reviewed; 310 AA.
AC Q8VGI6;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 127.
DE RecName: Full=Olfactory receptor 477;
DE AltName: Full=Olfactory receptor 204-1;
GN Name=Olfr477; Synonyms=Mor204-1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073162; AAL60825.1; -; Genomic_DNA.
DR EMBL; AY317585; AAP70981.1; -; Genomic_DNA.
DR CCDS; CCDS21699.1; -.
DR RefSeq; NP_667137.1; NM_146926.1.
DR AlphaFoldDB; Q8VGI6; -.
DR SMR; Q8VGI6; -.
DR STRING; 10090.ENSMUSP00000091654; -.
DR GlyGen; Q8VGI6; 3 sites.
DR iPTMnet; Q8VGI6; -.
DR PhosphoSitePlus; Q8VGI6; -.
DR PaxDb; Q8VGI6; -.
DR PRIDE; Q8VGI6; -.
DR DNASU; 258928; -.
DR Ensembl; ENSMUST00000091605; ENSMUSP00000091654; ENSMUSG00000096151.
DR Ensembl; ENSMUST00000214677; ENSMUSP00000150605; ENSMUSG00000096151.
DR GeneID; 258928; -.
DR KEGG; mmu:258928; -.
DR UCSC; uc009jbs.1; mouse.
DR CTD; 258928; -.
DR MGI; MGI:3030311; Olfr477.
DR VEuPathDB; HostDB:ENSMUSG00000096151; -.
DR eggNOG; ENOG502SKA1; Eukaryota.
DR GeneTree; ENSGT01050000244860; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VGI6; -.
DR OMA; FYSTRMC; -.
DR OrthoDB; 1013843at2759; -.
DR PhylomeDB; Q8VGI6; -.
DR TreeFam; TF338848; -.
DR BioGRID-ORCS; 258928; 1 hit in 46 CRISPR screens.
DR PRO; PR:Q8VGI6; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8VGI6; protein.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..310
FT /note="Olfactory receptor 477"
FT /id="PRO_0000150836"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 47..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..99
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..133
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..237
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 259..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..310
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 20
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 265
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..189
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 310 AA; 34141 MW; 5989CD56DF98E880 CRC64;
MEAQNHTTVK EFILLGLTEN STLRVILFMI FLGIYTVTLV GNFSIISLIR SCPQLHTPMY
LFLSHLALVD IGFSTSITPI MLTGFLGHTV TLSVAACVAQ FCIAVTFGTV ECFLLAVMAY
DRYVAICSPL LYSTHMSPRI CFLLVGASYV GGCVNSGTFT SCLLILSFCG PNQIDHFFCD
FPAVLKLSCS DVSIIGIIPS ISAGSIIVIT VFVIAVSYTY ILITILNMRS TEGRHKAFST
CTSHLTAVTL YYGTITFIYV MPKSNYSTAQ NKILSVFYTV VIPMLNPLIY SLRNRDVKEA
LRKAIIRIFP
