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OL478_MOUSE
ID   OL478_MOUSE             Reviewed;         314 AA.
AC   Q8VG04;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Olfactory receptor 478;
DE   AltName: Full=Olfactory receptor 204-13;
GN   Name=Olfr478; Synonyms=Mor204-13;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11802173; DOI=10.1038/nn800;
RA   Zhang X., Firestein S.;
RT   "The olfactory receptor gene superfamily of the mouse.";
RL   Nat. Neurosci. 5:124-133(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RT   "Different evolutionary processes shaped the mouse and human olfactory
RT   receptor gene families.";
RL   Hum. Mol. Genet. 11:535-546(2002).
RN   [3]
RP   ERRATUM OF PUBMED:11875048.
RA   Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA   Trask B.J.;
RL   Hum. Mol. Genet. 11:1683-1683(2002).
CC   -!- FUNCTION: Potential odorant receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; AY073361; AAL61024.1; -; Genomic_DNA.
DR   EMBL; AY317586; AAP70982.1; -; Genomic_DNA.
DR   CCDS; CCDS21700.1; -.
DR   RefSeq; NP_666945.1; NM_146734.1.
DR   RefSeq; XP_006507934.1; XM_006507871.1.
DR   AlphaFoldDB; Q8VG04; -.
DR   SMR; Q8VG04; -.
DR   STRING; 10090.ENSMUSP00000058931; -.
DR   GlyGen; Q8VG04; 1 site.
DR   iPTMnet; Q8VG04; -.
DR   PhosphoSitePlus; Q8VG04; -.
DR   PaxDb; Q8VG04; -.
DR   PRIDE; Q8VG04; -.
DR   DNASU; 258729; -.
DR   Ensembl; ENSMUST00000049719; ENSMUSP00000058931; ENSMUSG00000094426.
DR   Ensembl; ENSMUST00000210173; ENSMUSP00000147713; ENSMUSG00000094426.
DR   GeneID; 258729; -.
DR   KEGG; mmu:258729; -.
DR   UCSC; uc009jbt.1; mouse.
DR   CTD; 258729; -.
DR   MGI; MGI:3030312; Olfr478.
DR   VEuPathDB; HostDB:ENSMUSG00000094426; -.
DR   eggNOG; ENOG502SKA1; Eukaryota.
DR   GeneTree; ENSGT01050000244860; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; Q8VG04; -.
DR   OMA; FLVERNM; -.
DR   OrthoDB; 999769at2759; -.
DR   PhylomeDB; Q8VG04; -.
DR   TreeFam; TF338848; -.
DR   BioGRID-ORCS; 258729; 1 hit in 65 CRISPR screens.
DR   PRO; PR:Q8VG04; -.
DR   Proteomes; UP000000589; Chromosome 7.
DR   RNAct; Q8VG04; protein.
DR   Bgee; ENSMUSG00000094426; Expressed in embryonic brain and 10 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR   GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Olfactory receptor 478"
FT                   /id="PRO_0000150837"
FT   TOPO_DOM        1..28
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        29..49
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        50..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..78
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        79..102
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..136
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        137..157
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..199
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        221..240
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        241..261
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        262..274
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        296..314
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        8
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        100..192
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   314 AA;  34940 MW;  976122610A44A6EF CRC64;
     MAFQEDGNHT AVTEFVLFGL TDDPVLRVIL FIIFLCIYLV TVSGNLSTIL LIRVSSQLHH
     PMYFFLSHLA FADIGYSSSV TPNMLVNFLV ERHTISYIGC AIQLGSVVFF GSSECFILAA
     MAYDRFMAIC NPLLYSTKMS TQVCVQLLLI AYIGGFLNTW SFTICFYSLV FCGPNGVNHF
     FCDFAPLIEL SCSDVSVPAT VPSFTAGSII VVTVIVIAIS YIYILITILK MHSTEGRQKA
     FSTCTSHLTA VTLFYGTITF IYVMPKSSFS TDQNKVVSVF YMVVIPMLNP LIYSLRNNEI
     KGALKRQIGR KIFS
 
 
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