OL481_MOUSE
ID OL481_MOUSE Reviewed; 312 AA.
AC Q8VGI5;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Olfactory receptor 481;
DE AltName: Full=Olfactory receptor 204-2;
GN Name=Olfr481; Synonyms=Mor204-2;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073163; AAL60826.1; -; Genomic_DNA.
DR EMBL; AY317589; AAP70985.1; -; Genomic_DNA.
DR CCDS; CCDS21703.1; -.
DR RefSeq; NP_667136.1; NM_146925.1.
DR AlphaFoldDB; Q8VGI5; -.
DR SMR; Q8VGI5; -.
DR STRING; 10090.ENSMUSP00000063555; -.
DR GlyGen; Q8VGI5; 1 site.
DR PaxDb; Q8VGI5; -.
DR PRIDE; Q8VGI5; -.
DR DNASU; 258927; -.
DR Ensembl; ENSMUST00000067143; ENSMUSP00000063555; ENSMUSG00000054236.
DR Ensembl; ENSMUST00000213601; ENSMUSP00000151152; ENSMUSG00000054236.
DR GeneID; 258927; -.
DR KEGG; mmu:258927; -.
DR UCSC; uc009jbw.1; mouse.
DR CTD; 258927; -.
DR MGI; MGI:3030315; Olfr481.
DR VEuPathDB; HostDB:ENSMUSG00000054236; -.
DR eggNOG; ENOG502SKA1; Eukaryota.
DR GeneTree; ENSGT01050000244860; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VGI5; -.
DR OMA; NYSADQV; -.
DR OrthoDB; 924108at2759; -.
DR PhylomeDB; Q8VGI5; -.
DR TreeFam; TF352753; -.
DR BioGRID-ORCS; 258927; 3 hits in 67 CRISPR screens.
DR ChiTaRS; Olfr481; mouse.
DR PRO; PR:Q8VGI5; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8VGI5; protein.
DR Bgee; ENSMUSG00000054236; Expressed in embryonic facial prominence.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..312
FT /note="Olfactory receptor 481"
FT /id="PRO_0000150839"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 47..54
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..99
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..133
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..237
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 259..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..312
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..189
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 312 AA; 34348 MW; FC33A0E764744ACF CRC64;
METENDTMVT EFIILGLTDS ATLRAILFVF FLPVYIVTVV GNISIILLIR SSPQLHTPMY
LFLSHLAFVD IGYSTSVTPI MLISFLREET TIPLAGCAAQ LGSDVAFGTT ECFLLATMAY
DRYVAICSPL LYSTQMSPAI CCFLLGASYL GGCMNASSFT GCFVNLNFCG PNKVNHFFCD
LFPLVKLSCG HAYIAEISPS ISSASVLVST LSTIIVSYIY ILHSILRMRS AEGRNKAFST
CTSHLTAVTL FYGTVLFVYV MPKSSYSADQ VKVASVVYTV VIPMLNPLIY SLRNKEVKEA
MKKLMARTHW FP
