OL482_MOUSE
ID OL482_MOUSE Reviewed; 323 AA.
AC Q8VG03;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Olfactory receptor 482;
DE AltName: Full=Olfactory receptor 204-14;
GN Name=Olfr482; Synonyms=Mor204-14;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY073362; AAL61025.1; -; Genomic_DNA.
DR EMBL; AY317590; AAP70986.1; -; Genomic_DNA.
DR CCDS; CCDS21704.1; -.
DR RefSeq; NP_666944.1; NM_146733.1.
DR AlphaFoldDB; Q8VG03; -.
DR SMR; Q8VG03; -.
DR STRING; 10090.ENSMUSP00000079948; -.
DR GlyGen; Q8VG03; 3 sites.
DR PaxDb; Q8VG03; -.
DR PRIDE; Q8VG03; -.
DR DNASU; 258728; -.
DR Ensembl; ENSMUST00000081184; ENSMUSP00000079948; ENSMUSG00000059031.
DR Ensembl; ENSMUST00000217304; ENSMUSP00000150755; ENSMUSG00000059031.
DR GeneID; 258728; -.
DR KEGG; mmu:258728; -.
DR UCSC; uc009jbx.1; mouse.
DR CTD; 258728; -.
DR MGI; MGI:3030316; Olfr482.
DR VEuPathDB; HostDB:ENSMUSG00000059031; -.
DR eggNOG; ENOG502SKA1; Eukaryota.
DR GeneTree; ENSGT01050000244860; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VG03; -.
DR OMA; MSTEVCI; -.
DR OrthoDB; 999769at2759; -.
DR PhylomeDB; Q8VG03; -.
DR TreeFam; TF338848; -.
DR BioGRID-ORCS; 258728; 2 hits in 67 CRISPR screens.
DR ChiTaRS; Olfr482; mouse.
DR PRO; PR:Q8VG03; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8VG03; protein.
DR Bgee; ENSMUSG00000059031; Expressed in embryonic brain and 38 other tissues.
DR Genevisible; Q8VG03; MM.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..323
FT /note="Olfactory receptor 482"
FT /id="PRO_0000150840"
FT TOPO_DOM 1..28
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..102
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..136
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..199
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..220
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 221..240
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..261
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 262..274
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 275..295
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 296..323
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 8
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 92
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 268
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 100..192
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 323 AA; 35699 MW; 516CBE62BD6BF07C CRC64;
MAFLEDGNHT AVTEFILVGL TDDPVLKVIL FTIILCIYLV TVSGNLSTIL LIRVSSQLHH
PMYFFLSHLA SVDLGYSSSV TPNMLINFLA ENNTISYIGC SIQFGSATFF GVLECFLLAV
MAYDRFVAIC NPLLYSIKMS TQVCVKLVVG SYIGSSLNAS FVTVSIFNLL FCGPNKINHF
FCDFDPLIEL SCSDVSVPVA VTSCSAGLIT MITVFVIAVS YTYILITVLK MRSTEGRHKA
FSTCTSHLTA VTLFYGTVTF IYVMPKSNYS TDQNKVVSVF YMVVIPMLNP LIYSLRNNEI
KGALKRQLGK KIFSQSNILF CKS
