OL483_MOUSE
ID OL483_MOUSE Reviewed; 315 AA.
AC Q8VG05;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Olfactory receptor 483;
DE AltName: Full=Olfactory receptor 204-12;
GN Name=Olfr483; Synonyms=Mor204-12;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073360; AAL61023.1; -; Genomic_DNA.
DR EMBL; AY317591; AAP70987.1; -; Genomic_DNA.
DR CCDS; CCDS21705.1; -.
DR RefSeq; NP_666946.1; NM_146735.1.
DR AlphaFoldDB; Q8VG05; -.
DR SMR; Q8VG05; -.
DR STRING; 10090.ENSMUSP00000100517; -.
DR GlyGen; Q8VG05; 1 site.
DR PaxDb; Q8VG05; -.
DR PRIDE; Q8VG05; -.
DR DNASU; 258730; -.
DR Ensembl; ENSMUST00000104917; ENSMUSP00000100517; ENSMUSG00000078118.
DR Ensembl; ENSMUST00000215159; ENSMUSP00000150898; ENSMUSG00000078118.
DR GeneID; 258730; -.
DR KEGG; mmu:258730; -.
DR UCSC; uc009jby.1; mouse.
DR CTD; 258730; -.
DR MGI; MGI:3030317; Olfr483.
DR VEuPathDB; HostDB:ENSMUSG00000078118; -.
DR eggNOG; ENOG502SKA1; Eukaryota.
DR GeneTree; ENSGT01050000244860; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VG05; -.
DR OMA; ITYLRCG; -.
DR OrthoDB; 999769at2759; -.
DR PhylomeDB; Q8VG05; -.
DR TreeFam; TF338848; -.
DR BioGRID-ORCS; 258730; 0 hits in 65 CRISPR screens.
DR PRO; PR:Q8VG05; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8VG05; protein.
DR ExpressionAtlas; Q8VG05; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..315
FT /note="Olfactory receptor 483"
FT /id="PRO_0000150841"
FT TOPO_DOM 1..28
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..102
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..136
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..200
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 222..241
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 263..275
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 297..315
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 8
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 100..193
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 315 AA; 34774 MW; C775A89EC7674E0A CRC64;
MAFLQDGNHT AVTEFILLGL TDDPVLRVVL FTIILCIYLV TVFGNLSTIL LIRVSSQLHH
PMYFFLSHLA SVDIGISSSV TPSMLVNFLL ERSTISYLGC GIQLGSADFI ASVECFLLAA
MAYDRFMAVC NPLLYSTKMS TQVCVQLVVG SYIGGFLNAS LIVTVYFFSF LFCGPNRIDH
FFCDFAPLAE LSCSDVSVSV LIISFSAGSV TMITVFVIVI SYSYILITIL KMHSTEGRHK
AFSTCTSHLT AVTLYYGTIT FIYVMPKSSF STDQNKVVSV FYMVMIPMLN PLIYSLSNNE
IKGALKRQLG MKTLS
