OL507_MOUSE
ID OL507_MOUSE Reviewed; 316 AA.
AC Q8VG13;
DT 10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=Olfactory receptor 507;
DE AltName: Full=Olfactory receptor 204-7;
GN Name=Olfr507; Synonyms=Mor204-7;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11802173; DOI=10.1038/nn800;
RA Zhang X., Firestein S.;
RT "The olfactory receptor gene superfamily of the mouse.";
RL Nat. Neurosci. 5:124-133(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=11875048; DOI=10.1093/hmg/11.5.535;
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RT "Different evolutionary processes shaped the mouse and human olfactory
RT receptor gene families.";
RL Hum. Mol. Genet. 11:535-546(2002).
RN [3]
RP ERRATUM OF PUBMED:11875048.
RA Young J.M., Friedman C., Williams E.M., Ross J.A., Tonnes-Priddy L.,
RA Trask B.J.;
RL Hum. Mol. Genet. 11:1683-1683(2002).
CC -!- FUNCTION: Potential odorant receptor.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY073352; AAL61015.1; -; Genomic_DNA.
DR EMBL; AY317615; AAP71005.1; -; Genomic_DNA.
DR CCDS; CCDS21721.1; -.
DR RefSeq; NP_666954.1; NM_146743.1.
DR AlphaFoldDB; Q8VG13; -.
DR SMR; Q8VG13; -.
DR STRING; 10090.ENSMUSP00000078926; -.
DR GlyGen; Q8VG13; 1 site.
DR PaxDb; Q8VG13; -.
DR PRIDE; Q8VG13; -.
DR DNASU; 258738; -.
DR Ensembl; ENSMUST00000080014; ENSMUSP00000078926; ENSMUSG00000061000.
DR GeneID; 258738; -.
DR KEGG; mmu:258738; -.
DR UCSC; uc009jcq.1; mouse.
DR CTD; 258738; -.
DR MGI; MGI:3030341; Olfr507.
DR VEuPathDB; HostDB:ENSMUSG00000061000; -.
DR eggNOG; ENOG502SKA1; Eukaryota.
DR GeneTree; ENSGT01050000244860; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q8VG13; -.
DR OMA; IYLMTIC; -.
DR OrthoDB; 999769at2759; -.
DR PhylomeDB; Q8VG13; -.
DR TreeFam; TF338848; -.
DR BioGRID-ORCS; 258738; 4 hits in 66 CRISPR screens.
DR PRO; PR:Q8VG13; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q8VG13; protein.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..316
FT /note="Olfactory receptor 507"
FT /id="PRO_0000150854"
FT TOPO_DOM 1..28
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 29..49
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 50..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..102
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 103..123
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 124..136
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 158..199
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..220
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 221..240
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..261
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 262..274
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 275..297
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 298..316
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 8
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 100..192
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 316 AA; 34824 MW; 27C4E39DCA981DDB CRC64;
MGILKDGNHT AVTEFILLGL TDDPVLKVVL FTIILCIYLV TVSGNLSTIL LIRVSSQLHH
PMYFFLSHLA SVDIGISSSV TPNMLVNFLL ERSTISYLGC GIQLGSGAFF GSTESFLLAA
MAYDHFMAIC NPLLYSTKMS TQVCIQLLVG SYIGGFLNAS SFILSFFSFL FCGPNKVNHF
FCDFTPLVEL SCSDNSVLLI LDSFSAGSII VITVLVIAIS YTYILITILK MHSTEGRHKA
FSTCTSHLTA VTVFYGTVTF IYVMPKSSYS TDQNKVLSVF YMIAIAIPML NPLIYSLRNN
EIKNALKRQL SKKTFS
