OL867_MOUSE
ID OL867_MOUSE Reviewed; 331 AA.
AC Q7TRF3;
DT 20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Olfactory receptor 867;
GN Name=Olfr867 {ECO:0000312|EMBL:AAP71342.1, ECO:0000312|MGI:MGI:3030701};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000312|EMBL:AAP71342.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=14611657; DOI=10.1186/gb-2003-4-11-r71;
RA Young J.M., Shykind B.M., Lane R.P., Tonnes-Priddy L., Ross J.A.,
RA Walker M., Williams E.M., Trask B.J.;
RT "Odorant receptor expressed sequence tags demonstrate olfactory expression
RT of over 400 genes, extensive alternate splicing and unequal expression
RT levels.";
RL Genome Biol. 4:R71.1-R71.13(2003).
CC -!- FUNCTION: Possible olfactory or taste receptor.
CC {ECO:0000269|PubMed:14611657}.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR EMBL; AY318045; AAP71342.1; -; Genomic_DNA.
DR CCDS; CCDS22869.1; -.
DR RefSeq; NP_001011748.1; NM_001011748.1.
DR AlphaFoldDB; Q7TRF3; -.
DR SMR; Q7TRF3; -.
DR STRING; 10090.ENSMUSP00000057469; -.
DR GlyGen; Q7TRF3; 2 sites.
DR EPD; Q7TRF3; -.
DR PaxDb; Q7TRF3; -.
DR PRIDE; Q7TRF3; -.
DR ProteomicsDB; 294188; -.
DR DNASU; 257898; -.
DR Ensembl; ENSMUST00000060780; ENSMUSP00000057469; ENSMUSG00000044454.
DR Ensembl; ENSMUST00000216538; ENSMUSP00000150378; ENSMUSG00000044454.
DR GeneID; 257898; -.
DR KEGG; mmu:257898; -.
DR UCSC; uc009oia.1; mouse.
DR CTD; 257898; -.
DR MGI; MGI:3030701; Olfr867.
DR VEuPathDB; HostDB:ENSMUSG00000044454; -.
DR eggNOG; ENOG502QVH7; Eukaryota.
DR GeneTree; ENSGT00940000153686; -.
DR HOGENOM; CLU_012526_1_0_1; -.
DR InParanoid; Q7TRF3; -.
DR OMA; HTCISQF; -.
DR OrthoDB; 995191at2759; -.
DR PhylomeDB; Q7TRF3; -.
DR TreeFam; TF337210; -.
DR BioGRID-ORCS; 257898; 1 hit in 66 CRISPR screens.
DR PRO; PR:Q7TRF3; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q7TRF3; protein.
DR Bgee; ENSMUSG00000044454; Expressed in respiratory tract epithelium and 3 other tissues.
DR ExpressionAtlas; Q7TRF3; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; ISA:MGI.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0004984; F:olfactory receptor activity; ISA:MGI.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; ISA:MGI.
DR GO; GO:0007608; P:sensory perception of smell; ISA:MGI.
DR GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000725; Olfact_rcpt.
DR Pfam; PF13853; 7tm_4; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00245; OLFACTORYR.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..331
FT /note="Olfactory receptor 867"
FT /id="PRO_0000280220"
FT TOPO_DOM 1..25
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 26..46
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 47..57
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 79..97
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 119..142
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 164..196
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..244
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 266..271
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 272..292
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 293..331
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 5
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 167
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 97..179
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ SEQUENCE 331 AA; 37660 MW; E5897320AE535C10 CRC64;
MEIENHTLIT KFLILGLSDD PELQPILFGL FLSMYLVTLL GNLLIILAVS SDSHLHKPMY
FLLSNLSFID ICFISTTIPK MLVNMQSQIK DISYIECLTQ VFFFNIFAGM DNFLLTLMAY
DRFVAICHPL NYTVIMNPRL CALLILMFWI IMFWVSLIHV LLMNELNFSR GTEIPHFFCE
LAQVLKVSNS DNHVNNVFMY VVTSLLGVIP MTGILMSYSQ IFSSLFRMSS TVSKYKAFST
CGSHLCVVTL FYGSGFGVYF SSSVVHSTQR RKVASLMYTV ISPMLNPFIY TLRNKDVKGA
LGKLFNRVAS SPSCINDIRN KLLLRSVRQI L
