ID   ART10_YEAS8             Reviewed;         518 AA.
AC   C8ZE01;
DT   30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-NOV-2009, sequence version 1.
DT   25-MAY-2022, entry version 30.
DE   RecName: Full=Arrestin-related trafficking adapter 10;
GN   Name=ART10; ORFNames=EC1118_1L7_2685g;
OS   Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS   yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=643680;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lalvin EC1118 / Prise de mousse;
RX   PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA   Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA   Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT   "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT   sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC   -!- FUNCTION: May regulate endocytosis by recruiting RSP5 ubiquitin ligase
CC       activity to specific plasma membrane proteins in response to
CC       extracellular stimuli. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with RSP5. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Ubiquitinated by RSP5. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ART10 family. {ECO:0000305}.
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DR   EMBL; FN393080; CAY81617.1; -; Genomic_DNA.
DR   AlphaFoldDB; C8ZE01; -.
DR   EnsemblFungi; CAY81617; CAY81617; EC1118_1L7_2685g.
DR   HOGENOM; CLU_540776_0_0_1; -.
DR   Proteomes; UP000000286; Chromosome XII, Scaffold EC1118_1L7.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.640; -; 1.
DR   InterPro; IPR014752; Arrestin-like_C.
PE   3: Inferred from homology;
KW   Cytoplasm; Endocytosis; Isopeptide bond; Ubl conjugation.
FT   CHAIN           1..518
FT                   /note="Arrestin-related trafficking adapter 10"
FT                   /id="PRO_0000402196"
FT   CROSSLNK        118
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in ubiquitin)"
FT                   /evidence="ECO:0000250|UniProtKB:P18634"
SQ   SEQUENCE   518 AA;  59779 MW;  5048F50792BB80B4 CRC64;
     MAPKISISLN PPYNGEFYSS NDQMSGIVSL QLTKALSIRK ISVILKGFSE TLTKIDQEYM
     FQQNGMMMPG QDNKSFHTLM KFEQRVFPPD NVWNALDGSS KPFKVKPGSY NYSFQFEKFP
     RKPECLKNHT AKTVAFVTRN NARLPPTFNS HWQEFNKIDN LDLYFYSFGK VIYMVQVQIE
     LGKSSSWFKP FHKLIREIET FEFIPEPKDL IVEPDEDDNE ELNAFSNNSR GNSLVTNNEF
     FNSSNLKVPS KDVKVVNGVG YIKSDRNFSQ ANSILIENGD IRSRPVSSVT STRQSTRLVN
     GMKVFPSTYK MGLPDGESNM RIEVRSRDLK QIYRKDYLFR SGSQNFDKVY VVMEGNIASL
     SKMQITPLKL QLNLLETTTY LSQGIANGNY SSLKLIEIDL NQLKSNKPLL DLNEIRENFD
     GSMFECELRL KDHPILRKLV FNEEDYRHRG NRLYSFKTCT IKRIFSLQLL IEWGINGIRK
     QSEVNIDPVQ IFCQVREHVE AEALPRYVPP PTYTEMAS