ART1_SCHPO
ID ART1_SCHPO Reviewed; 483 AA.
AC O42956;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Arrestin family protein 1;
GN Name=art1; ORFNames=SPBC19G7.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP FUNCTION.
RX PubMed=20739711; DOI=10.1534/genetics.110.119842;
RA Wu J.Q., Ye Y., Wang N., Pollard T.D., Pringle J.R.;
RT "Cooperation between the septins and the actomyosin ring and role of a
RT cell-integrity pathway during cell division in fission yeast.";
RL Genetics 186:897-915(2010).
CC -!- FUNCTION: Involved in cytokinesis. {ECO:0000269|PubMed:20739711}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR EMBL; CU329671; CAA17062.1; -; Genomic_DNA.
DR PIR; T39839; T39839.
DR RefSeq; NP_595974.1; NM_001021882.2.
DR AlphaFoldDB; O42956; -.
DR BioGRID; 277265; 16.
DR STRING; 4896.SPBC19G7.08c.1; -.
DR MaxQB; O42956; -.
DR PaxDb; O42956; -.
DR EnsemblFungi; SPBC19G7.08c.1; SPBC19G7.08c.1:pep; SPBC19G7.08c.
DR GeneID; 2540742; -.
DR KEGG; spo:SPBC19G7.08c; -.
DR PomBase; SPBC19G7.08c; art1.
DR VEuPathDB; FungiDB:SPBC19G7.08c; -.
DR eggNOG; ENOG502RX7P; Eukaryota.
DR HOGENOM; CLU_589451_0_0_1; -.
DR InParanoid; O42956; -.
DR OMA; WSMDLPF; -.
DR PRO; PR:O42956; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0032153; C:cell division site; IDA:PomBase.
DR GO; GO:0005737; C:cytoplasm; IDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0000935; C:division septum; IDA:PomBase.
DR GO; GO:0005509; F:calcium ion binding; ISM:PomBase.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; EXP:PomBase.
DR GO; GO:0000917; P:division septum assembly; IBA:GO_Central.
DR GO; GO:0140278; P:mitotic division septum assembly; IMP:PomBase.
DR Gene3D; 2.60.40.640; -; 1.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011022; Arrestin_C-like.
DR Pfam; PF02752; Arrestin_C; 1.
DR SMART; SM01017; Arrestin_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome.
FT CHAIN 1..483
FT /note="Arrestin family protein 1"
FT /id="PRO_0000303891"
FT REGION 134..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 483 AA; 53711 MW; 74F8FAC7FAE1807A CRC64;
MTSPCTLIRQ FSPLEIRPLP HLDFQAGFNG IPTSAPRLVG IVQVRSKEIH QPLALVQITL
ELWKIESVVI PSLGISNHLS DNKCLARQVL FPLHSEHPEN NIPPNDNNYS ISDLSIKSPP
PSLTSDWIVD SYASDQDNPS VHTHNRTTPP IPPPHLPNAS GSSVYQPPYT PFRSVSTTSS
SNDTSITPFG DQTPILSSSS DPYATHRVWS MDLPFEIPFP ENSEIPSTFE LNRSGTICST
KYELRAHMSL LGVPDITTTV PVSLSRYDNL SSWGMYNSPT NIRQVSSDGR VVVEVSIPKL
CIGPSDLVSV FVSIMPNNGS KIRVQQLSLS LVEYITFIHP SSSSPIVRKK KVLRYEEDLD
DMKLTSEGLS KSLSKPFPDI DFEDANITGF TTTSDLYSVQ YMLVIKVQLY RARNIEITNP
IIVSPVERSR SQALLNEIQT RVLDVRQSHG GVVLEENVRI VRASDFSKNN MFAYLNDDIV
LLS
