ID   OLF1_CANLF              Reviewed;         311 AA.
AC   Q95154;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Olfactory receptor-like protein OLF1;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8855279; DOI=10.1073/pnas.93.20.10897;
RA   Issel-Tarver L., Rine J.;
RT   "Organization and expression of canine olfactory receptor genes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:10897-10902(1996).
CC   -!- FUNCTION: Putative odorant or sperm cell receptor.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; U53679; AAB37239.1; -; Genomic_DNA.
DR   RefSeq; NP_001013438.1; NM_001013420.1.
DR   AlphaFoldDB; Q95154; -.
DR   SMR; Q95154; -.
DR   STRING; 9612.ENSCAFP00000038802; -.
DR   PaxDb; Q95154; -.
DR   Ensembl; ENSCAFT00030007297; ENSCAFP00030006396; ENSCAFG00030003962.
DR   Ensembl; ENSCAFT00845012180; ENSCAFP00845009520; ENSCAFG00845006861.
DR   GeneID; 483548; -.
DR   CTD; 10798; -.
DR   VEuPathDB; HostDB:ENSCAFG00845006861; -.
DR   eggNOG; ENOG502SIQS; Eukaryota.
DR   GeneTree; ENSGT01050000244804; -.
DR   OrthoDB; 952595at2759; -.
DR   Proteomes; UP000002254; Chromosome 18.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0005549; F:odorant binding; IBA:GO_Central.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0007608; P:sensory perception of smell; IBA:GO_Central.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; G-protein coupled receptor; Glycoprotein; Membrane;
KW   Olfaction; Receptor; Reference proteome; Sensory transduction; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..311
FT                   /note="Olfactory receptor-like protein OLF1"
FT                   /id="PRO_0000150799"
FT   TOPO_DOM        1..24
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        25..48
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        49..56
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..78
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        79..99
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        100..119
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        120..138
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..157
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        158..195
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..218
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        219..235
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..259
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        260..271
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..291
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        292..311
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        4
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   311 AA;  35210 MW;  05A2132474F543A1 CRC64;
     MDGNYTLVTE FILLGFPTRP ELQIVLFLVF LTLYGIILTG NIGLMMLIRT DPHLQTPMYF
     FLSNLSFADL CFSSAIVPKM LVNFLSENKS ISLYGCALQF YFSCAFADTE SFILAAMAYD
     RYVAICNPLL YTVVMSRGIC VWLIVLSYIG GNMSSLVHTS FAFILKYCDK NVINHFFCDL
     PPLLKLSCTD TSVNEWLLST YGSSVEIFCF IVIVISYYFI LRSVLRIRSS SGRKKTFSTC
     ASHLTSVAIY QGTLLFIYSR PTYLYTPNTD KIISVFYTII IPVLNPLIYS LRNKDVKDAA
     KRAVRLKVDS S