ID   OLM2A_XENTR             Reviewed;         642 AA.
AC   A4IIT5;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Olfactomedin-like protein 2A;
DE   Flags: Precursor;
GN   Name=olfml2a;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:Q8BHP7}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:Q8BHP7}.
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DR   EMBL; BC136146; AAI36147.1; -; mRNA.
DR   RefSeq; NP_001096445.1; NM_001102975.1.
DR   AlphaFoldDB; A4IIT5; -.
DR   SMR; A4IIT5; -.
DR   PaxDb; A4IIT5; -.
DR   GeneID; 100125057; -.
DR   KEGG; xtr:100125057; -.
DR   CTD; 169611; -.
DR   Xenbase; XB-GENE-996424; olfml2a.
DR   eggNOG; KOG3545; Eukaryota.
DR   InParanoid; A4IIT5; -.
DR   OrthoDB; 311650at2759; -.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR003112; Olfac-like_dom.
DR   InterPro; IPR031231; OLFML2A.
DR   PANTHER; PTHR23192:SF29; PTHR23192:SF29; 1.
DR   Pfam; PF02191; OLF; 1.
DR   SMART; SM00284; OLF; 1.
DR   PROSITE; PS51132; OLF; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Disulfide bond; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..642
FT                   /note="Olfactomedin-like protein 2A"
FT                   /id="PRO_0000311431"
FT   DOMAIN          385..642
FT                   /note="Olfactomedin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00446"
FT   REGION          211..265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          285..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          330..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          150..176
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        219..249
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        386..572
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00446"
SQ   SEQUENCE   642 AA;  73007 MW;  687A75D67FD8C766 CRC64;
     MWDYKHFLLL SLAFTSTVTA LSKVLGDTDQ VRMTSEGSDC RCKCIMRPLS KEACSRVKGG
     NMRVEDYYTV ETVSSGSDCK CSCTAPPSSL NPCENEWKME KMKKQAPELF KLQSMVDLLE
     GTLYSMDLMK VHSYINKVVS QMNTLEETIK TNLTRENDFM KESVVNLSNQ MKKYENYSEI
     MLSIKKEISN LGYQLLQKDA PENKAQDTAG VKGLAKFPNN KKNEGDKSLS KVTKDKPPKA
     EKPKKEVSKT KQVPPQPTPR PRSPVLQPVV IRGVTYYKAG RQEDAENAAG NRESVVKGPH
     RGAKQEIRTE GNITEPYLIR EERIVATQRA TPTPTPTTTP TTTQSTTTTT TTRTTISTAT
     EYPLTTLSST VLGAEAETNK VREGECEGTI ASVEQPKKQH SYGRNEGAWM KDPIAKDGRI
     YVTNYYYGNN LVEFRNLDNF KQGRWSNLYK VPYNWIGTGH VVFQGAFYYN RAFTKNIIKY
     DLKQRFVAAW TLLHDVVYED TTPWKWRGHS DIDFAVDESG LWVIYPSVDY DYSQQEVIVI
     SKLDPNDLSI KKETTWKTGL KRNSYGNCFI ICGILYAVDV YNQKEGMISY AYDTHTDTEA
     DPKLPFINEY AFTTQIDYNP KEKVLYAWDN GHQLTYKVNF VA