ID   OLM2B_BOVIN             Reviewed;         759 AA.
AC   A6QLD2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Olfactomedin-like protein 2B;
DE   Flags: Precursor;
GN   Name=OLFML2B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal muscle;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer. Binds to heparin and chondroitin sulfate E (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- PTM: O-glycosylated and N-glycosylated. {ECO:0000250}.
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DR   EMBL; BC147922; AAI47923.1; -; mRNA.
DR   RefSeq; NP_001093824.1; NM_001100354.1.
DR   AlphaFoldDB; A6QLD2; -.
DR   SMR; A6QLD2; -.
DR   STRING; 9913.ENSBTAP00000015933; -.
DR   PaxDb; A6QLD2; -.
DR   PRIDE; A6QLD2; -.
DR   Ensembl; ENSBTAT00000015933; ENSBTAP00000015933; ENSBTAG00000034147.
DR   GeneID; 513053; -.
DR   KEGG; bta:513053; -.
DR   CTD; 25903; -.
DR   VEuPathDB; HostDB:ENSBTAG00000034147; -.
DR   VGNC; VGNC:32423; OLFML2B.
DR   eggNOG; KOG3545; Eukaryota.
DR   GeneTree; ENSGT00940000157757; -.
DR   HOGENOM; CLU_024107_0_0_1; -.
DR   InParanoid; A6QLD2; -.
DR   OMA; FFEYHEF; -.
DR   OrthoDB; 311650at2759; -.
DR   TreeFam; TF351220; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000034147; Expressed in trachea and 101 other tissues.
DR   GO; GO:0031012; C:extracellular matrix; IEA:Ensembl.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0050840; F:extracellular matrix binding; IEA:Ensembl.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0030198; P:extracellular matrix organization; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   InterPro; IPR003112; Olfac-like_dom.
DR   InterPro; IPR031233; OLFML2B.
DR   PANTHER; PTHR23192:SF37; PTHR23192:SF37; 1.
DR   Pfam; PF02191; OLF; 1.
DR   SMART; SM00284; OLF; 1.
DR   PROSITE; PS51132; OLF; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Disulfide bond; Glycoprotein; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000250"
FT   CHAIN           21..759
FT                   /note="Olfactomedin-like protein 2B"
FT                   /id="PRO_0000311425"
FT   DOMAIN          502..759
FT                   /note="Olfactomedin-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00446"
FT   REGION          346..396
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          456..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          40..68
FT                   /evidence="ECO:0000255"
FT   COILED          179..209
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        358..396
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        187
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        213
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        704
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        503..689
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00446"
SQ   SEQUENCE   759 AA;  84493 MW;  3DDDB6E5E2A2F25A CRC64;
     MAKSLLLVLC FALVTTLGWG YSAPPTGTTE PPDVQTVAPT EDETLQNEAD NQENVLSQLL
     GDYDKVKAVS EGSDCQCKCV VRPLGRDACQ RVNAGTSRKE DFYTVETITS GPSCKCACVA
     PPSALNPCEG DFRLQKLREA DSRDLKLSTI IDMLEGAFYG LDLLKLHSVT TKLVGRVDKL
     EEEISKNLTK ENEQIREDVE EIRTEMNKRG KENCSNNILD SIPDIRSALQ RDAAAAYTHP
     EYEERFLQEE TVSQQIKSIK LLQTRPLAPP EVVKPQRPLQ RQVHLRGRPA SRPTVIRGIT
     YYKAKDPEEE NDIEEHQDEF FSGEHGMDLL IEDQLLRHNQ LLTSATRRPA ATGRSAAVTA
     DAGTTSAGTP TTALPSARLP ASTAAPSTPD PAVSASVEQF STPLPTTSVS PDPTEEAVPT
     PFTQVPATTV AHTATQQPPA SAPPSAAPED AFVEATHTAP VPPPPVRTDS PGKDSTARQG
     TVPPGPTLSP EEEDDIRNVI GRCKDTLSTI TGPITQNTYG RNEGAWMKDP LAKDERIYVT
     NYYYGNTLVE FRNLENFKQG RWSNSYKLPY SWIGTGHVVY NGAFYYNRAF TRNIIKYDLK
     QRYVAAWAML HDVAYEEATP WRWQGHSDVD FAVDENGLWL IYPALDDEGF SQEVIVLSKL
     NAVDLSTQKE TTWRTGLRRN LYGNCFVICG VLYAVDSHNQ RNANISYAFD THTNTQIVPR
     LLFENEYSYT TQIDYNPKDR LLYAWDNGHQ VTYHVIFAY