ARTI_ECOLI
ID ARTI_ECOLI Reviewed; 243 AA.
AC P30859; P77640;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 3.
DT 03-AUG-2022, entry version 160.
DE RecName: Full=Putative ABC transporter arginine-binding protein 2;
DE Flags: Precursor;
GN Name=artI; OrderedLocusNames=b0863, JW0847;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / AN387;
RX PubMed=8501075; DOI=10.1128/jb.175.11.3687-3688.1993;
RA Wissenbach U., Unden G.;
RT "Physical map location of the new artPIQMJ genes of Escherichia coli,
RT encoding a periplasmic arginine transport system.";
RL J. Bacteriol. 175:3687-3688(1993).
RN [2]
RP SEQUENCE REVISION TO 48.
RC STRAIN=K12 / AN387;
RA Wissenbach U., Unden G.;
RL Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [6]
RP PROTEIN SEQUENCE OF 20-29, FUNCTION, SUBUNIT, AND SUBCELLULAR LOCATION.
RX PubMed=8801422; DOI=10.1111/j.1365-2958.1995.mmi_17040675.x;
RA Wissenbach U., Six S., Bongaerts J., Ternes D., Steinwachs S., Unden G.;
RT "A third periplasmic transport system for L-arginine in Escherichia coli:
RT molecular characterization of the artPIQMJ genes, arginine binding and
RT transport.";
RL Mol. Microbiol. 17:675-686(1995).
RN [7]
RP PROTEIN SEQUENCE OF 20-31.
RC STRAIN=K12 / EMG2;
RX PubMed=9298646; DOI=10.1002/elps.1150180807;
RA Link A.J., Robison K., Church G.M.;
RT "Comparing the predicted and observed properties of proteins encoded in the
RT genome of Escherichia coli K-12.";
RL Electrophoresis 18:1259-1313(1997).
RN [8]
RP PROTEIN SEQUENCE OF 20-23.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9600841; DOI=10.1006/jmbi.1998.1726;
RA Wilkins M.R., Gasteiger E., Tonella L., Ou K., Tyler M., Sanchez J.-C.,
RA Gooley A.A., Walsh B.J., Bairoch A., Appel R.D., Williams K.L.,
RA Hochstrasser D.F.;
RT "Protein identification with N and C-terminal sequence tags in proteome
RT projects.";
RL J. Mol. Biol. 278:599-608(1998).
CC -!- FUNCTION: Part of the ABC transporter complex ArtPIQMJ involved in
CC arginine transport. {ECO:0000269|PubMed:8801422}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (ArtP),
CC two transmembrane proteins (ArtM and ArtQ) and two solute-binding
CC proteins (ArtJ and ArtI). {ECO:0000305|PubMed:8801422}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000269|PubMed:8801422}.
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 3 family.
CC {ECO:0000305}.
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DR EMBL; X86160; CAA60102.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73950.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35577.1; -; Genomic_DNA.
DR PIR; G64824; G64824.
DR RefSeq; NP_415384.1; NC_000913.3.
DR RefSeq; WP_000756569.1; NZ_STEB01000019.1.
DR AlphaFoldDB; P30859; -.
DR SMR; P30859; -.
DR BioGRID; 4263132; 15.
DR ComplexPortal; CPX-4318; Arginine ABC transporter complex, artI variant.
DR IntAct; P30859; 4.
DR STRING; 511145.b0863; -.
DR TCDB; 3.A.1.3.3; the atp-binding cassette (abc) superfamily.
DR SWISS-2DPAGE; P30859; -.
DR jPOST; P30859; -.
DR PaxDb; P30859; -.
DR PRIDE; P30859; -.
DR EnsemblBacteria; AAC73950; AAC73950; b0863.
DR EnsemblBacteria; BAA35577; BAA35577; BAA35577.
DR GeneID; 66670863; -.
DR GeneID; 948988; -.
DR KEGG; ecj:JW0847; -.
DR KEGG; eco:b0863; -.
DR PATRIC; fig|1411691.4.peg.1414; -.
DR EchoBASE; EB1582; -.
DR eggNOG; COG0834; Bacteria.
DR HOGENOM; CLU_019602_18_0_6; -.
DR InParanoid; P30859; -.
DR OMA; DTPFENF; -.
DR PhylomeDB; P30859; -.
DR BioCyc; EcoCyc:ARTI-MON; -.
DR PRO; PR:P30859; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IDA:EcoCyc.
DR GO; GO:0042597; C:periplasmic space; IDA:EcoliWiki.
DR GO; GO:0015276; F:ligand-gated ion channel activity; IEA:InterPro.
DR GO; GO:0097638; P:L-arginine import across plasma membrane; IC:ComplexPortal.
DR InterPro; IPR001320; Iontro_rcpt.
DR InterPro; IPR005768; Lys_Arg_Orn-bd.
DR InterPro; IPR018313; SBP_3_CS.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00062; PBPb; 1.
DR SMART; SM00079; PBPe; 1.
DR TIGRFAMs; TIGR01096; 3A0103s03R; 1.
DR PROSITE; PS01039; SBP_BACTERIAL_3; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; Direct protein sequencing; Periplasm;
KW Reference proteome; Signal; Transport.
FT SIGNAL 1..19
FT /evidence="ECO:0000269|PubMed:8801422,
FT ECO:0000269|PubMed:9298646, ECO:0000269|PubMed:9600841"
FT CHAIN 20..243
FT /note="Putative ABC transporter arginine-binding protein 2"
FT /id="PRO_0000031751"
FT CONFLICT 48
FT /note="V -> VV (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 86
FT /note="A -> G (in Ref. 1; CAA60102)"
FT /evidence="ECO:0000305"
FT CONFLICT 130
FT /note="G -> RS (in Ref. 1; CAA60102)"
FT /evidence="ECO:0000305"
FT CONFLICT 164
FT /note="Q -> E (in Ref. 1; CAA60102)"
FT /evidence="ECO:0000305"
FT CONFLICT 179
FT /note="T -> H (in Ref. 1; CAA60102)"
FT /evidence="ECO:0000305"
FT CONFLICT 189..190
FT /note="AA -> VV (in Ref. 1; CAA60102)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 243 AA; 26930 MW; 15C56F7E5AD115C2 CRC64;
MKKVLIAALI AGFSLSATAA ETIRFATEAS YPPFESIDAN NQIVGFDVDL AQALCKEIDA
TCTFSNQAFD SLIPSLKFRR VEAVMAGMDI TPEREKQVLF TTPYYDNSAL FVGQQGKYTS
VDQLKGKKVG VQNGTTHQKF IMDKHPEITT VPYDSYQNAK LDLQNGRIDG VFGDTAVVTE
WLKDNPKLAA VGDKVTDKDY FGTGLGIAVR QGNTELQQKL NTALEKVKKD GTYETIYNKW
FQK
