OM25_BRUME
ID OM25_BRUME Reviewed; 213 AA.
AC Q45321;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=25 kDa outer-membrane immunogenic protein;
DE Flags: Precursor;
GN Name=omp25; OrderedLocusNames=BMEI1249;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=8675306; DOI=10.1128/iai.64.6.2047-2055.1996;
RA Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.;
RT "Nucleotide sequence and expression of the gene encoding the major 25-
RT kilodalton outer membrane protein of Brucella ovis: evidence for antigenic
RT shift, compared with other Brucella species, due to a deletion in the
RT gene.";
RL Infect. Immun. 64:2047-2055(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC -!- SIMILARITY: Belongs to the Omp25/RopB family. {ECO:0000305}.
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DR EMBL; U33003; AAB06701.1; -; Genomic_DNA.
DR EMBL; AE008917; AAL52430.1; -; Genomic_DNA.
DR PIR; AC3408; AC3408.
DR RefSeq; WP_004683466.1; NZ_GG703778.1.
DR AlphaFoldDB; Q45321; -.
DR SMR; Q45321; -.
DR STRING; 224914.BMEI1249; -.
DR EnsemblBacteria; AAL52430; AAL52430; BMEI1249.
DR GeneID; 29594100; -.
DR KEGG; bme:BMEI1249; -.
DR PATRIC; fig|224914.52.peg.164; -.
DR eggNOG; COG3637; Bacteria.
DR OMA; RVGYDMN; -.
DR PhylomeDB; Q45321; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044384; C:host outer membrane; IEA:InterPro.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000758; Enterovir_OMP.
DR InterPro; IPR011250; OMP/PagP_b-brl.
DR InterPro; IPR027385; OMP_b-brl.
DR Pfam; PF13505; OMP_b-brl; 1.
DR SUPFAM; SSF56925; SSF56925; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal; Transmembrane;
KW Transmembrane beta strand.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..213
FT /note="25 kDa outer-membrane immunogenic protein"
FT /id="PRO_0000021880"
SQ SEQUENCE 213 AA; 23185 MW; 59003CF46F6D0ED3 CRC64;
MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT GLYLGYGWNK
AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGDAGYS WAKKSKDGLE VKQGFEGSLR
ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD DESKFRVGWT AGAGLEAKLT DNILGRVEYR
YTQYGNKNYD LAGTTVRNKL DTQDFRVGIG YKF