OM25_BRUO2
ID OM25_BRUO2 Reviewed; 201 AA.
AC Q45335; A5VPN5;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=25 kDa outer-membrane immunogenic protein;
DE Flags: Precursor;
GN Name=omp25; OrderedLocusNames=BOV_0692;
OS Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=444178;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8675306; DOI=10.1128/iai.64.6.2047-2055.1996;
RA Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.;
RT "Nucleotide sequence and expression of the gene encoding the major 25-
RT kilodalton outer membrane protein of Brucella ovis: evidence for antigenic
RT shift, compared with other Brucella species, due to a deletion in the
RT gene.";
RL Infect. Immun. 64:2047-2055(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25840 / 63/290 / NCTC 10512;
RX PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT "Genome degradation in Brucella ovis corresponds with narrowing of its host
RT range and tissue tropism.";
RL PLoS ONE 4:E5519-E5519(2009).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC -!- DOMAIN: Has a C-terminal deletion compared to that of other Brucella
CC species.
CC -!- SIMILARITY: Belongs to the Omp25/RopB family. {ECO:0000305}.
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DR EMBL; U33004; AAB06702.1; -; Genomic_DNA.
DR EMBL; CP000708; ABQ61895.1; -; Genomic_DNA.
DR RefSeq; WP_006012064.1; NC_009505.1.
DR AlphaFoldDB; Q45335; -.
DR SMR; Q45335; -.
DR EnsemblBacteria; ABQ61895; ABQ61895; BOV_0692.
DR GeneID; 45124148; -.
DR KEGG; bov:BOV_0692; -.
DR HOGENOM; CLU_037100_4_0_5; -.
DR OMA; RVGYDMN; -.
DR PhylomeDB; Q45335; -.
DR PRO; PR:Q45335; -.
DR Proteomes; UP000006383; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR011250; OMP/PagP_b-brl.
DR InterPro; IPR027385; OMP_b-brl.
DR Pfam; PF13505; OMP_b-brl; 1.
DR SUPFAM; SSF56925; SSF56925; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Membrane; Signal; Transmembrane;
KW Transmembrane beta strand.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..201
FT /note="25 kDa outer-membrane immunogenic protein"
FT /id="PRO_0000021882"
SQ SEQUENCE 201 AA; 21817 MW; 85A4897489A0935B CRC64;
MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT GLYLGYGWNK
AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGNAGYS WAKKSKDGLE VKQGFEGSLR
ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD DESKFRVGWT AGAGLEAKLT DNILGRVEYR
YTQYGNKLDT QDIRVGIGYK F