ID   OM25_BRUSU              Reviewed;         213 AA.
AC   Q45689; G0K8C0;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=25 kDa outer-membrane immunogenic protein;
DE   Flags: Precursor;
GN   Name=omp25; OrderedLocusNames=BR0701, BS1330_I0697;
OS   Brucella suis biovar 1 (strain 1330).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=204722;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=8675306; DOI=10.1128/iai.64.6.2047-2055.1996;
RA   Cloeckaert A., Verger J.M., Grayon M., Zygmunt M.S., Grepinet O.;
RT   "Nucleotide sequence and expression of the gene encoding the major 25-
RT   kilodalton outer membrane protein of Brucella ovis: evidence for antigenic
RT   shift, compared with other Brucella species, due to a deletion in the
RT   gene.";
RL   Infect. Immun. 64:2047-2055(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=12271122; DOI=10.1073/pnas.192319099;
RA   Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA   Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA   Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA   Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA   Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT   "The Brucella suis genome reveals fundamental similarities between animal
RT   and plant pathogens and symbionts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=22038969; DOI=10.1128/jb.06181-11;
RA   Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT   "Revised genome sequence of Brucella suis 1330.";
RL   J. Bacteriol. 193:6410-6410(2011).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- SIMILARITY: Belongs to the Omp25/RopB family. {ECO:0000305}.
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DR   EMBL; U39397; AAB36695.1; -; Genomic_DNA.
DR   EMBL; AE014291; AAN29630.1; -; Genomic_DNA.
DR   EMBL; CP002997; AEM18047.1; -; Genomic_DNA.
DR   RefSeq; WP_002963844.1; NZ_KN046804.1.
DR   AlphaFoldDB; Q45689; -.
DR   SMR; Q45689; -.
DR   EnsemblBacteria; AEM18047; AEM18047; BS1330_I0697.
DR   GeneID; 45051781; -.
DR   KEGG; bms:BR0701; -.
DR   KEGG; bsi:BS1330_I0697; -.
DR   PATRIC; fig|204722.22.peg.1143; -.
DR   HOGENOM; CLU_037100_4_0_5; -.
DR   OMA; RVGYDMN; -.
DR   PhylomeDB; Q45689; -.
DR   PRO; PR:Q45689; -.
DR   Proteomes; UP000007104; Chromosome I.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR027385; OMP_b-brl.
DR   Pfam; PF13505; OMP_b-brl; 1.
DR   SUPFAM; SSF56925; SSF56925; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..213
FT                   /note="25 kDa outer-membrane immunogenic protein"
FT                   /id="PRO_0000021883"
SQ   SEQUENCE   213 AA;  23151 MW;  55F33CF46F6D0ED3 CRC64;
     MRTLKSLVIV SAALLPFSAT AFAADAIQEQ PPVPAPVEVA PQYSWAGGYT GLYLGYGWNK
     AKTSTVGSIK PDDWKAGAFA GWNFQQDQIV YGVEGDAGYS WAKKSKDGLE VKQGFEGSLR
     ARVGYDLNPV MPYLTAGIAG SQIKLNNGLD DESKFRVGWT AGAGLEAKLT DNILGRVEYR
     YTQYGNKNYD LAGTTVRNKL DTQDIRVGIG YKF