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OM31_BRUME
ID   OM31_BRUME              Reviewed;         240 AA.
AC   P0A3U4; Q45322;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=31 kDa outer-membrane immunogenic protein;
DE   Flags: Precursor;
GN   Name=omp31; OrderedLocusNames=BMEII0844;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=8751924; DOI=10.1128/iai.64.9.3744-3751.1996;
RA   Vizcaino N., Cloeckaert A., Zygmunt M.S., Dubray G.;
RT   "Cloning, nucleotide sequence, and expression of the Brucella melitensis
RT   omp31 gene coding for an immunogenic major outer membrane protein.";
RL   Infect. Immun. 64:3744-3751(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- FUNCTION: Major outer membrane protein associated with peptidoglycans.
CC       May function as a porin.
CC   -!- SUBUNIT: Oligomeric.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- SIMILARITY: Belongs to the Omp25/RopB family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL54086.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF076290; AAB36693.1; -; Genomic_DNA.
DR   EMBL; AE008918; AAL54086.1; ALT_INIT; Genomic_DNA.
DR   PIR; AC3615; AC3615.
DR   RefSeq; WP_004681766.1; NZ_GG703779.1.
DR   AlphaFoldDB; P0A3U4; -.
DR   STRING; 224914.BMEII0844; -.
DR   TCDB; 1.B.4.2.15; the brucella-rhizobium porin (brp) family.
DR   EnsemblBacteria; AAL54086; AAL54086; BMEII0844.
DR   GeneID; 45053476; -.
DR   KEGG; bme:BMEII0844; -.
DR   PATRIC; fig|224914.52.peg.2520; -.
DR   eggNOG; COG3637; Bacteria.
DR   OMA; ATHIGWT; -.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR027385; OMP_b-brl.
DR   Pfam; PF13505; OMP_b-brl; 1.
DR   SUPFAM; SSF56925; SSF56925; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..240
FT                   /note="31 kDa outer-membrane immunogenic protein"
FT                   /id="PRO_0000021884"
FT   REGION          48..83
FT                   /note="Epitope recognized by the monoclonal antibody
FT                   A59/10F09/G10"
SQ   SEQUENCE   240 AA;  25323 MW;  21C6E5EC479F66A5 CRC64;
     MKSVILASIA AMFATSAMAA DVVVSEPSAP TAAPVDTFSW TGGYIGINAG YAGGKFKHPF
     SSFDKEDNEQ VSGSLDVTAG GFVGGVQAGY NWQLDNGVVL GAETDFQGSS VTGSISAGAS
     GLEGKAETKV EWFGTVRARL GYTATERLMV YGTGGLAYGK VKSAFNLGDD ASALHTWSDK
     TKAGWTLGAG AEYAINNNWT LKSEYLYTDL GKRNLVDVDN SFLESKVNFH TVRVGLNYKF
 
 
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