OMP19_BRUA2
ID OMP19_BRUA2 Reviewed; 177 AA.
AC Q2YLR6; P0A3P3; Q44663; Q44699; Q57AW8;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Outer membrane lipoprotein omp19;
DE AltName: Full=18 kDa immunoreactive antigen;
DE AltName: Full=19 kDa OMP;
DE AltName: Full=Minor outer membrane protein omp19;
DE Flags: Precursor;
GN Name=omp19; OrderedLocusNames=BAB1_1930;
OS Brucella abortus (strain 2308).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=359391;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9140920; DOI=10.1006/mpat.1996.0108;
RA Kovach M.E., Elzer P.H., Robertson G.T., Chirhart-Gilleland R.L.,
RA Christensen M.A., Peterson K.M., Roop R.M. II;
RT "Cloning and nucleotide sequence analysis of a Brucella abortus gene
RT encoding an 18 kDa immunoreactive protein.";
RL Microb. Pathog. 22:241-246(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2308;
RX PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL Infect. Immun. 73:8353-8361(2005).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC -!- MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and
CC goats infected with B.melitensis or B.abortus, but not in B.abortus-
CC infected cattle.
CC -!- SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family.
CC {ECO:0000305}.
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DR EMBL; U35742; AAB04100.1; -; Genomic_DNA.
DR EMBL; AM040264; CAJ11886.1; -; Genomic_DNA.
DR RefSeq; WP_002964998.1; NZ_KN046823.1.
DR AlphaFoldDB; Q2YLR6; -.
DR SMR; Q2YLR6; -.
DR STRING; 359391.BAB1_1930; -.
DR EnsemblBacteria; CAJ11886; CAJ11886; BAB1_1930.
DR GeneID; 45052878; -.
DR GeneID; 55591519; -.
DR KEGG; bmf:BAB1_1930; -.
DR PATRIC; fig|359391.11.peg.1170; -.
DR HOGENOM; CLU_103254_0_0_5; -.
DR OMA; CRIATPQ; -.
DR PRO; PR:Q2YLR6; -.
DR Proteomes; UP000002719; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR010571; OM_lipoprot_Omp19_bac.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR PIRSF; PIRSF034005; OM_lipoprot_Omp19_bac; 1.
DR SUPFAM; SSF50882; SSF50882; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000305"
FT CHAIN 21..177
FT /note="Outer membrane lipoprotein omp19"
FT /id="PRO_0000096164"
FT REGION 28..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
FT CONFLICT 176..177
FT /note="SR -> LG (in Ref. 1; AAB04100)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 177 AA; 17604 MW; 8038D5ABD87019E2 CRC64;
MGISKASLLS LAAAGIVLAG CQSSRLGNLD NVSPPPPPAP VNAVPAGTVQ KGNLDSPTQF
PNAPSTDMSA QSGTQVASLP PASAPDLTPG AVAGVWNASL GGQSCKIATP QTKYGQGYRA
GPLRCPGELA NLASWAVNGK QLVLYDANGG TVASLYSSGQ GRFDGQTTGG QAVTLSR
