OMP19_BRUAB
ID OMP19_BRUAB Reviewed; 177 AA.
AC P0C109; P0A3P3; Q44663; Q44699; Q57AW8;
DT 07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Outer membrane lipoprotein omp19;
DE AltName: Full=18 kDa immunoreactive antigen;
DE AltName: Full=19 kDa OMP;
DE AltName: Full=Minor outer membrane protein omp19;
DE Flags: Precursor;
GN Name=omp19; OrderedLocusNames=BruAb1_1906;
OS Brucella abortus biovar 1 (strain 9-941).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=262698;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=544 / Biovar 1;
RX PubMed=8557326; DOI=10.1128/iai.64.1.100-107.1996;
RA Tibor A., Saman E., de Wergifosse P., Cloeckaert A., Limet J.N.,
RA Letesson J.-J.;
RT "Molecular characterization, occurrence, and immunogenicity in infected
RT sheep and cattle of two minor outer membrane proteins of Brucella
RT abortus.";
RL Infect. Immun. 64:100-107(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9-941;
RX PubMed=15805518; DOI=10.1128/jb.187.8.2715-2726.2005;
RA Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z.,
RA Li L.-L., Kapur V., Alt D.P., Olsen S.C.;
RT "Completion of the genome sequence of Brucella abortus and comparison to
RT the highly similar genomes of Brucella melitensis and Brucella suis.";
RL J. Bacteriol. 187:2715-2726(2005).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC -!- MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and
CC goats infected with B.melitensis or B.abortus, but not in B.abortus-
CC infected cattle.
CC -!- SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family.
CC {ECO:0000305}.
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DR EMBL; L27997; AAB06277.1; -; Genomic_DNA.
DR EMBL; AE017223; AAX75216.1; -; Genomic_DNA.
DR RefSeq; WP_002964998.1; NC_006932.1.
DR AlphaFoldDB; P0C109; -.
DR SMR; P0C109; -.
DR EnsemblBacteria; AAX75216; AAX75216; BruAb1_1906.
DR GeneID; 45052878; -.
DR GeneID; 55591519; -.
DR KEGG; bmb:BruAb1_1906; -.
DR HOGENOM; CLU_103254_0_0_5; -.
DR OMA; CRIATPQ; -.
DR PRO; PR:P0C109; -.
DR Proteomes; UP000000540; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR010571; OM_lipoprot_Omp19_bac.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR PIRSF; PIRSF034005; OM_lipoprot_Omp19_bac; 1.
DR SUPFAM; SSF50882; SSF50882; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000305"
FT CHAIN 21..177
FT /note="Outer membrane lipoprotein omp19"
FT /id="PRO_0000018243"
FT REGION 28..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 177 AA; 17604 MW; 8038D5ABD87019E2 CRC64;
MGISKASLLS LAAAGIVLAG CQSSRLGNLD NVSPPPPPAP VNAVPAGTVQ KGNLDSPTQF
PNAPSTDMSA QSGTQVASLP PASAPDLTPG AVAGVWNASL GGQSCKIATP QTKYGQGYRA
GPLRCPGELA NLASWAVNGK QLVLYDANGG TVASLYSSGQ GRFDGQTTGG QAVTLSR
