OMP19_BRUME
ID OMP19_BRUME Reviewed; 177 AA.
AC P0A3P1; Q44663; Q44699;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Outer membrane lipoprotein omp19;
DE AltName: Full=18 kDa immunoreactive antigen;
DE AltName: Full=19 kDa OMP;
DE AltName: Full=Minor outer membrane protein omp19;
DE Flags: Precursor;
GN Name=omp19; OrderedLocusNames=BMEI0135;
OS Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=224914;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / NCTC 10094;
RX PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen Brucella
RT melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC -!- MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and
CC goats infected with B.melitensis or B.abortus, but not in B.abortus-
CC infected cattle.
CC -!- SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family.
CC {ECO:0000305}.
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DR EMBL; AE008917; AAL51317.1; -; Genomic_DNA.
DR PIR; AB3269; AB3269.
DR RefSeq; WP_002964998.1; NZ_GG703778.1.
DR AlphaFoldDB; P0A3P1; -.
DR SMR; P0A3P1; -.
DR STRING; 224914.BMEI0135; -.
DR EnsemblBacteria; AAL51317; AAL51317; BMEI0135.
DR GeneID; 45052878; -.
DR GeneID; 55591519; -.
DR KEGG; bme:BMEI0135; -.
DR PATRIC; fig|224914.52.peg.1371; -.
DR eggNOG; ENOG503363Z; Bacteria.
DR OMA; CRIATPQ; -.
DR Proteomes; UP000000419; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR010571; OM_lipoprot_Omp19_bac.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR PIRSF; PIRSF034005; OM_lipoprot_Omp19_bac; 1.
DR SUPFAM; SSF50882; SSF50882; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000305"
FT CHAIN 21..177
FT /note="Outer membrane lipoprotein omp19"
FT /id="PRO_0000018244"
FT REGION 28..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 177 AA; 17604 MW; 8038D5ABD87019E2 CRC64;
MGISKASLLS LAAAGIVLAG CQSSRLGNLD NVSPPPPPAP VNAVPAGTVQ KGNLDSPTQF
PNAPSTDMSA QSGTQVASLP PASAPDLTPG AVAGVWNASL GGQSCKIATP QTKYGQGYRA
GPLRCPGELA NLASWAVNGK QLVLYDANGG TVASLYSSGQ GRFDGQTTGG QAVTLSR
