OMP19_BRUSU
ID OMP19_BRUSU Reviewed; 177 AA.
AC P0A3P2; G0K873; Q44663; Q44699;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Outer membrane lipoprotein omp19;
DE AltName: Full=18 kDa immunoreactive antigen;
DE AltName: Full=19 kDa OMP;
DE AltName: Full=Minor outer membrane protein omp19;
DE Flags: Precursor;
GN Name=omp19; OrderedLocusNames=BR1930, BS1330_I1924;
OS Brucella suis biovar 1 (strain 1330).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX NCBI_TaxID=204722;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=12271122; DOI=10.1073/pnas.192319099;
RA Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT "The Brucella suis genome reveals fundamental similarities between animal
RT and plant pathogens and symbionts.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1330;
RX PubMed=22038969; DOI=10.1128/jb.06181-11;
RA Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT "Revised genome sequence of Brucella suis 1330.";
RL J. Bacteriol. 193:6410-6410(2011).
CC -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC -!- MISCELLANEOUS: Elicits an immune response in humans, mice, sheep and
CC goats infected with B.melitensis or B.abortus, but not in B.abortus-
CC infected cattle.
CC -!- SIMILARITY: Belongs to the rhizobiaceae omp19 lipoprotein family.
CC {ECO:0000305}.
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DR EMBL; AE014291; AAN30822.1; -; Genomic_DNA.
DR EMBL; CP002997; AEM19239.1; -; Genomic_DNA.
DR RefSeq; WP_002964998.1; NZ_KN046804.1.
DR AlphaFoldDB; P0A3P2; -.
DR SMR; P0A3P2; -.
DR EnsemblBacteria; AEM19239; AEM19239; BS1330_I1924.
DR GeneID; 45052878; -.
DR GeneID; 55591519; -.
DR KEGG; bms:BR1930; -.
DR KEGG; bsi:BS1330_I1924; -.
DR PATRIC; fig|204722.21.peg.2981; -.
DR HOGENOM; CLU_103254_0_0_5; -.
DR OMA; CRIATPQ; -.
DR PRO; PR:P0A3P2; -.
DR Proteomes; UP000007104; Chromosome I.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR010571; OM_lipoprot_Omp19_bac.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR PIRSF; PIRSF034005; OM_lipoprot_Omp19_bac; 1.
DR SUPFAM; SSF50882; SSF50882; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000305"
FT CHAIN 21..177
FT /note="Outer membrane lipoprotein omp19"
FT /id="PRO_0000018245"
FT REGION 28..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 21
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000305"
FT LIPID 21
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000305"
SQ SEQUENCE 177 AA; 17604 MW; 8038D5ABD87019E2 CRC64;
MGISKASLLS LAAAGIVLAG CQSSRLGNLD NVSPPPPPAP VNAVPAGTVQ KGNLDSPTQF
PNAPSTDMSA QSGTQVASLP PASAPDLTPG AVAGVWNASL GGQSCKIATP QTKYGQGYRA
GPLRCPGELA NLASWAVNGK QLVLYDANGG TVASLYSSGQ GRFDGQTTGG QAVTLSR
