ID   OMP2B_BRUO2             Reviewed;         367 AA.
AC   A5VPH9;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Porin Omp2b;
DE   Flags: Precursor;
GN   Name=omp2a; OrderedLocusNames=BOV_0634;
OS   Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=444178;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25840 / 63/290 / NCTC 10512;
RX   PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA   Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA   de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA   Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA   Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT   "Genome degradation in Brucella ovis corresponds with narrowing of its host
RT   range and tissue tropism.";
RL   PLoS ONE 4:E5519-E5519(2009).
CC   -!- FUNCTION: Forms passive diffusion pores that allow small molecular
CC       weight hydrophilic materials across the outer membrane.
CC       {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- DOMAIN: Consists of 16-stranded beta-barrel sheets, with large surface-
CC       exposed loops, that form a transmembrane pore at the center of each
CC       barrel. The pore is partially ocluded by a peptide loop that folds into
CC       the pore lumen. {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SIMILARITY: Belongs to the alphaproteobacteria porin family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABQ60409.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000708; ABQ60409.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_006159548.1; NC_009505.1.
DR   AlphaFoldDB; A5VPH9; -.
DR   EnsemblBacteria; ABQ60409; ABQ60409; BOV_0634.
DR   GeneID; 45124093; -.
DR   KEGG; bov:BOV_0634; -.
DR   HOGENOM; CLU_044836_0_0_5; -.
DR   PhylomeDB; A5VPH9; -.
DR   Proteomes; UP000006383; Chromosome I.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003684; Porin_alphabac.
DR   Pfam; PF02530; Porin_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..367
FT                   /note="Porin Omp2b"
FT                   /id="PRO_0000354017"
SQ   SEQUENCE   367 AA;  39562 MW;  807BEB16981A76C5 CRC64;
     MNIKSLLLGS AAALVAASGA QAADAIVAPE PEAVEYVRVC DAYGAGYFYI PGTETCLRIS
     GYVRYDVKGG DDVYTGSDRK GWDKGARFAL MFNTNSETEL GTLGTYTQLR FNYTSNNSRH
     DGQYGDFSDD RDVADGSVST GTDLQFAYIT LGGFKVGIDE SEFHTFTGYL GDIINDDVIS
     AGSYRTGKIA YTFTGGNGFS AVIALEQGGE DVDNDYTIDG YMPHVVGGLK YAGGWGSIAG
     VVAYDSVIEE WATKVRGDVN ITDRFSVWLQ GAYSSAATPN QNYGQWGGDW AVWGGLKYQA
     TQKAAFNLQA AHDDWGKTAV TANVAYELVP GFTVTPEVSY TKFGGEWKNT VAEDNAWGGI
     VRFQRSF