ID   OMP2B_BRUSI             Reviewed;         362 AA.
AC   B0CKW5;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 2.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Porin Omp2b;
DE   Flags: Precursor;
GN   Name=omp2b; OrderedLocusNames=BSUIS_A0667;
OS   Brucella suis (strain ATCC 23445 / NCTC 10510).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=470137;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23445 / NCTC 10510;
RA   Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J., Dharmanolla C.,
RA   Gillespie J.J., Kenyon R.W., Lu J., Mane S., Mohapatra S., Nagrani S.,
RA   Purkayastha A., Rajasimha H.K., Shallom J.M., Shallom S., Shukla M.,
RA   Snyder E.E., Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H.,
RA   Bruce D., Detter C., Munk C., Brettin T.S.;
RT   "Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms passive diffusion pores that allow small molecular
CC       weight hydrophilic materials across the outer membrane.
CC       {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000250|UniProtKB:Q44665}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:Q44665}.
CC   -!- DOMAIN: Consists of 16-stranded beta-barrel sheets, with large surface-
CC       exposed loops, that form a transmembrane pore at the center of each
CC       barrel. The pore is partially ocluded by a peptide loop that folds into
CC       the pore lumen. {ECO:0000250|UniProtKB:Q44665}.
CC   -!- SIMILARITY: Belongs to the alphaproteobacteria porin family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABY37745.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000911; ABY37745.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_006072430.1; NC_010169.1.
DR   AlphaFoldDB; B0CKW5; -.
DR   EnsemblBacteria; ABY37745; ABY37745; BSUIS_A0667.
DR   KEGG; bmt:BSUIS_A0667; -.
DR   HOGENOM; CLU_044836_0_0_5; -.
DR   Proteomes; UP000008545; Chromosome I.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003684; Porin_alphabac.
DR   Pfam; PF02530; Porin_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..362
FT                   /note="Porin Omp2b"
FT                   /id="PRO_0000354020"
SQ   SEQUENCE   362 AA;  38814 MW;  BAD7B3AF65C0E439 CRC64;
     MNIKSLLLGS AAALVAASGA QAADAIVAPE PEAVEYVRVC DAYGAGYFYI PGTETCLRVH
     GYVRYDVKGG DDVYTGSDRK GWDKGARFAL MFNTNSETEL GTLKTFTELR FNYAANNSGV
     DGKYGNETSS GTVMEFAYIQ LGGLRVGIDE SEFHTFTGYL GDVINDDVIS AGSYRTGKIS
     YTFTGGNGFS AVIALEQGGD NDGGYTGTTN YHIDGYMPDV VGGLKYAGGW GSIAGVVAYD
     SVIEEWAAKV RGDVNITDQF SVWLQGAYSS AATPDQNYGQ WGGDWAVWGG LKYQATQKAA
     FNLQAAHDDW GKTAVTANVA YELVPGFTVT PEVSYTKFGG EWKNTVAEDN AWGGIVRFQR
     SF