ID   OMP41_PORGI             Reviewed;         391 AA.
AC   Q9S3R9;
DT   17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2003, sequence version 2.
DT   03-AUG-2022, entry version 122.
DE   RecName: Full=Outer membrane protein 41;
DE            Short=Omp41;
DE   AltName: Full=PG32;
DE   Flags: Precursor;
GN   OrderedLocusNames=PG_0695;
OS   Porphyromonas gingivalis (strain ATCC BAA-308 / W83).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC   Porphyromonas.
OX   NCBI_TaxID=242619;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 53978 / W50;
RX   PubMed=11457538; DOI=10.1016/s0264-410x(01)00173-6;
RA   Ross B.C., Czajkowski L., Hocking D., Margetts M., Webb E., Rothel L.,
RA   Patterson M., Agius C., Camuglia S., Reynolds E.C., Littlejohn T.,
RA   Gaeta B., Ng A., Kuczek E.S., Mattick J.S., Gearing D.P., Barr I.G.;
RT   "Identification of vaccine candidate antigens from a genomic analysis of
RT   Porphyromonas gingivalis.";
RL   Vaccine 19:4135-4142(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-308 / W83;
RX   PubMed=12949112; DOI=10.1128/jb.185.18.5591-5601.2003;
RA   Nelson K.E., Fleischmann R.D., DeBoy R.T., Paulsen I.T., Fouts D.E.,
RA   Eisen J.A., Daugherty S.C., Dodson R.J., Durkin A.S., Gwinn M.L.,
RA   Haft D.H., Kolonay J.F., Nelson W.C., Mason T.M., Tallon L., Gray J.,
RA   Granger D., Tettelin H., Dong H., Galvin J.L., Duncan M.J., Dewhirst F.E.,
RA   Fraser C.M.;
RT   "Complete genome sequence of the oral pathogenic bacterium Porphyromonas
RT   gingivalis strain W83.";
RL   J. Bacteriol. 185:5591-5601(2003).
RN   [3] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 21-391, AND PYROGLUTAMATE FORMATION AT GLN-21.
RC   STRAIN=ATCC 53978 / W50;
RX   PubMed=11532011; DOI=10.1046/j.1432-1327.2001.02399.x;
RA   Veith P.D., Talbo G.H., Slakeski N., Reynolds E.C.;
RT   "Identification of a novel heterodimeric outer membrane protein of
RT   Porphyromonas gingivalis by two-dimensional gel electrophoresis and peptide
RT   mass fingerprinting.";
RL   Eur. J. Biochem. 268:4748-4757(2001).
CC   -!- FUNCTION: May have porin activity and function in peptidoglycan
CC       binding. {ECO:0000303|PubMed:11532011}.
CC   -!- SUBUNIT: Disulfide-linked heterodimer with Omp40.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AF175714; AAD51067.1; -; Genomic_DNA.
DR   EMBL; AE015924; AAQ65868.1; -; Genomic_DNA.
DR   RefSeq; WP_005873612.1; NC_002950.2.
DR   AlphaFoldDB; Q9S3R9; -.
DR   SMR; Q9S3R9; -.
DR   STRING; 242619.PG_0695; -.
DR   PRIDE; Q9S3R9; -.
DR   EnsemblBacteria; AAQ65868; AAQ65868; PG_0695.
DR   KEGG; pgi:PG_0695; -.
DR   eggNOG; COG2885; Bacteria.
DR   HOGENOM; CLU_058370_1_0_10; -.
DR   OMA; RYRISKR; -.
DR   OrthoDB; 583204at2; -.
DR   Proteomes; UP000000588; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019867; C:outer membrane; IDA:UniProtKB.
DR   GO; GO:0030247; F:polysaccharide binding; TAS:UniProtKB.
DR   GO; GO:0015288; F:porin activity; TAS:UniProtKB.
DR   CDD; cd07185; OmpA_C-like; 1.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   InterPro; IPR006664; OMP_bac.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR006690; OMPA-like_CS.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   Pfam; PF00691; OmpA; 1.
DR   PRINTS; PR01021; OMPADOMAIN.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   PROSITE; PS01068; OMPA_1; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Direct protein sequencing; Disulfide bond; Membrane;
KW   Pyrrolidone carboxylic acid; Reference proteome; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000269|PubMed:11532011"
FT   CHAIN           21..391
FT                   /note="Outer membrane protein 41"
FT                   /id="PRO_0000020114"
FT   DOMAIN          282..391
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
FT   MOD_RES         21
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:11532011"
FT   CONFLICT        45
FT                   /note="S -> R (in Ref. 1; AAD51067)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        324
FT                   /note="I -> V (in Ref. 1; AAD51067)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   391 AA;  43424 MW;  4E595BDB7F7C7736 CRC64;
     MKVKYLMLTL VGAIALNASA QENTVPATGQ LPAKNVAFAR NKAGSNWFVT LQGGVAAQFL
     NDNNNKDLMD RLGAIGSLSV GKYHSPFFAT RLQINGGQAH TFLGKNGEQE INTNFGAAHF
     DFMFDVVNYF APYRENRFFH LIPWVGVGYQ HKFIGSEWSK DNVESLTANV GVMMAFRLGK
     RVDFVIEAQA AHSNLNLSRA YNAKKTPVFE DPAGRYYNGF QGMATAGLNF RLGAVGFNAI
     EPMDYALIND LNGQINRLRS EVEELSKRPV SCPECPEVTP VTKTENILTE KAVLFRFDSH
     VVDKDQLINL YDVAQFVKET NEPITVVGYA DPTGNTQYNE KLSERRAKAV VDVLTGKYGV
     PSELISVEWK GDSTQPFSKK AWNRVVIVRS K