ID   OMP4_NEIMA              Reviewed;         242 AA.
AC   P0A0V2; A1ITT6; P38367;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Outer membrane protein class 4;
DE   Flags: Precursor;
GN   Name=rmpM; OrderedLocusNames=NMA2105;
OS   Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS   Z2491).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122587;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15465 / Z2491;
RX   PubMed=10761919; DOI=10.1038/35006655;
RA   Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA   Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA   Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA   Barrell B.G.;
RT   "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT   Z2491.";
RL   Nature 404:502-506(2000).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000250|UniProtKB:P0A910}; Multi-pass membrane protein
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL157959; CAM09205.1; -; Genomic_DNA.
DR   PIR; A81782; A81782.
DR   RefSeq; WP_002226062.1; NC_003116.1.
DR   AlphaFoldDB; P0A0V2; -.
DR   SMR; P0A0V2; -.
DR   PRIDE; P0A0V2; -.
DR   EnsemblBacteria; CAM09205; CAM09205; NMA2105.
DR   KEGG; nma:NMA2105; -.
DR   HOGENOM; CLU_016890_5_0_4; -.
DR   OMA; CWRTGYW; -.
DR   BioCyc; NMEN122587:NMA_RS10710-MON; -.
DR   EvolutionaryTrace; P0A0V2; -.
DR   Proteomes; UP000000626; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd07185; OmpA_C-like; 1.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   InterPro; IPR006664; OMP_bac.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR006690; OMPA-like_CS.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   Pfam; PF00691; OmpA; 1.
DR   PRINTS; PR01021; OMPADOMAIN.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   PROSITE; PS01068; OMPA_1; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Ion transport; Membrane; Porin;
KW   Repeat; Signal; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..242
FT                   /note="Outer membrane protein class 4"
FT                   /id="PRO_0000020111"
FT   REPEAT          69..70
FT                   /note="1"
FT   REPEAT          71..72
FT                   /note="2"
FT   REPEAT          73..74
FT                   /note="3"
FT   REPEAT          75..76
FT                   /note="4"
FT   REPEAT          77..78
FT                   /note="5"
FT   REPEAT          79..80
FT                   /note="6"
FT   REPEAT          81..82
FT                   /note="7"
FT   DOMAIN          92..229
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
FT   REGION          69..82
FT                   /note="7 X 2 AA tandem repeats of X-P"
FT   DISULFID        191..214
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   242 AA;  26141 MW;  5CCAA490236B1D62 CRC64;
     MTKQLKLSAL FVALLASGTA VAGEASVQGY TVSGQSNEIV RNNYGECWKN AYFDKASQGR
     VECGDAVAAP EPEPEPEPAP APVVVVEQAP QYVDETISLS AKTLFGFDKD SLRAEAQDNL
     KVLAQRLGQT NIQSVRVEGH TDFMGSDKYN QALSERRAYV VANNLVSNGV PVSRISAVGL
     GESQAQMTQV CEAEVAKLGA KVSKAKKREA LIACIEPDRR VDVKIRSIVT RQVVPAHNHH
     QH