ID   OMP7_STAAE              Reviewed;         584 AA.
AC   A6QIG2; P21223; Q9K4S8;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=65 kDa membrane protein;
DE   AltName: Full=map-ND2C;
DE   Flags: Precursor;
GN   OrderedLocusNames=NWMN_1872;
OS   Staphylococcus aureus (strain Newman).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=426430;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11687475; DOI=10.1128/cdli.8.6.1271-1276.2001;
RA   Hussain M., Becker K., von Eiff C., Peters G., Herrmann M.;
RT   "Analogs of Eap protein are conserved and prevalent in clinical
RT   Staphylococcus aureus isolates.";
RL   Clin. Diagn. Lab. Immunol. 8:1271-1276(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Newman;
RX   PubMed=17951380; DOI=10.1128/jb.01000-07;
RA   Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.;
RT   "Genome sequence of Staphylococcus aureus strain Newman and comparative
RT   analysis of staphylococcal genomes: polymorphism and evolution of two major
RT   pathogenicity islands.";
RL   J. Bacteriol. 190:300-310(2008).
RN   [3]
RP   PROTEIN SEQUENCE OF 31-53.
RA   Hussain M.S., Herrmann M., Chhatwal G.S., Peters G.;
RT   "Map-n protein deficient mutant of Staphylococcus aureus Newman binds less
RT   to fibronectin and collagen coated surfaces. A 70 kDa vitronectin protein
RT   of Staphylococcus aureus Newman.";
RL   Submitted (FEB-1999) to UniProtKB.
CC   -!- FUNCTION: Binds various plasma and ECM-proteins.
CC   -!- SUBCELLULAR LOCATION: Cell membrane.
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DR   EMBL; AJ290973; CAB94853.1; -; Genomic_DNA.
DR   EMBL; AP009351; BAF68144.1; -; Genomic_DNA.
DR   RefSeq; WP_001549158.1; NZ_CP023390.1.
DR   AlphaFoldDB; A6QIG2; -.
DR   SMR; A6QIG2; -.
DR   EnsemblBacteria; BAF68144; BAF68144; NWMN_1872.
DR   KEGG; sae:NWMN_1872; -.
DR   HOGENOM; CLU_466842_0_0_9; -.
DR   OMA; HHGYSKI; -.
DR   Proteomes; UP000006386; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005298; MAP_dom.
DR   Pfam; PF03642; MAP; 5.
DR   PROSITE; PS51223; MAP; 5.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Membrane; Repeat; Signal.
FT   SIGNAL          1..30
FT                   /evidence="ECO:0000255"
FT   CHAIN           31..584
FT                   /note="65 kDa membrane protein"
FT                   /id="PRO_0000324108"
FT   REPEAT          45..154
FT                   /note="MAP 1"
FT   REPEAT          156..265
FT                   /note="MAP 2"
FT   REPEAT          266..374
FT                   /note="MAP 3"
FT   REPEAT          375..474
FT                   /note="MAP 4"
FT   REPEAT          475..584
FT                   /note="MAP 5"
FT   CONFLICT        124
FT                   /note="A -> V (in Ref. 1; CAB94853)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        434
FT                   /note="T -> A (in Ref. 1; CAB94853)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        543
FT                   /note="K -> R (in Ref. 1; CAB94853)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        571
FT                   /note="D -> G (in Ref. 1; CAB94853)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   584 AA;  65574 MW;  014F81175CE48273 CRC64;
     MKFKSLITTT LALGVLASTG ANFNNNEASA AAKPLDKSSS SLHHGYSKVH VPYAITVNGT
     SQNILSSLTF NKNQNISYKD LEDRVKSVLK SDRGISDIDL RLSKQAKYTV YFKNGTKKVI
     DLKAGIYTAD LINTSEIKAI NINVDTKKQV EDKKKDKANY QVPYTITVNG TSQNILSNLT
     FNKNQNISYK DLEDKVKSVL ESNRGITDVD LRLSKQAKYT VNFKNGTKKV IDLKSGIYTA
     NLINSSDIKS ININVDTKKH IENKAKRNYQ VPYSINLNGT STNILSNLSF SNKPWTNYKN
     LTSQIKSVLK HDRGISEQDL KYAKKAYYTV YFKNGGKRIL QLNSKNYTAN LVHAKDVKRI
     EITVKTGTKA KADRYVPYTI AVNGTSTPIL SDLKFTGDPR VGYKDISKKV KSVLKHDRGI
     GERELKYAKK ATYTVHFKNG TKKVININSN ISQLNLLYVQ DIKKIDIDVK TGTKAKADSY
     VPYTIAVNGT STPILSKLKI SNKQLISYKY LNDKVKSVLK SERGISDLDL KFAKQAKYTV
     YFKNGKKQVV NLKSDIFTPN LFSAKDIKKI DIDVKQYTKS KKNK