ARTP_ECOLI
ID ARTP_ECOLI Reviewed; 242 AA.
AC P0AAF6; P30858; P77355;
DT 11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Arginine transport ATP-binding protein ArtP;
DE EC=7.4.2.-;
GN Name=artP; OrderedLocusNames=b0864, JW0848;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / AN387;
RX PubMed=8501075; DOI=10.1128/jb.175.11.3687-3688.1993;
RA Wissenbach U., Unden G.;
RT "Physical map location of the new artPIQMJ genes of Escherichia coli,
RT encoding a periplasmic arginine transport system.";
RL J. Bacteriol. 175:3687-3688(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP FUNCTION, AND SUBUNIT.
RX PubMed=8801422; DOI=10.1111/j.1365-2958.1995.mmi_17040675.x;
RA Wissenbach U., Six S., Bongaerts J., Ternes D., Steinwachs S., Unden G.;
RT "A third periplasmic transport system for L-arginine in Escherichia coli:
RT molecular characterization of the artPIQMJ genes, arginine binding and
RT transport.";
RL Mol. Microbiol. 17:675-686(1995).
CC -!- FUNCTION: Part of the ABC transporter complex ArtPIQMJ involved in
CC arginine transport. Probably responsible for energy coupling to the
CC transport system. {ECO:0000269|PubMed:8801422}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (ArtP),
CC two transmembrane proteins (ArtM and ArtQ) and two solute-binding
CC proteins (ArtJ and ArtI). {ECO:0000305|PubMed:8801422}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Peripheral
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR EMBL; X86160; CAA60101.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73951.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35578.1; -; Genomic_DNA.
DR PIR; H64824; H64824.
DR RefSeq; NP_415385.1; NC_000913.3.
DR RefSeq; WP_000027205.1; NZ_STEB01000019.1.
DR AlphaFoldDB; P0AAF6; -.
DR SMR; P0AAF6; -.
DR BioGRID; 4263133; 11.
DR BioGRID; 849863; 6.
DR ComplexPortal; CPX-4318; Arginine ABC transporter complex, artI variant.
DR ComplexPortal; CPX-4319; Arginine ABC transporter complex, artJ variant.
DR DIP; DIP-47917N; -.
DR IntAct; P0AAF6; 12.
DR STRING; 511145.b0864; -.
DR TCDB; 3.A.1.3.3; the atp-binding cassette (abc) superfamily.
DR jPOST; P0AAF6; -.
DR PaxDb; P0AAF6; -.
DR PRIDE; P0AAF6; -.
DR EnsemblBacteria; AAC73951; AAC73951; b0864.
DR EnsemblBacteria; BAA35578; BAA35578; BAA35578.
DR GeneID; 66670862; -.
DR GeneID; 945489; -.
DR KEGG; ecj:JW0848; -.
DR KEGG; eco:b0864; -.
DR PATRIC; fig|1411691.4.peg.1413; -.
DR EchoBASE; EB1581; -.
DR eggNOG; COG1126; Bacteria.
DR HOGENOM; CLU_000604_1_22_6; -.
DR InParanoid; P0AAF6; -.
DR OMA; ATMLKPN; -.
DR PhylomeDB; P0AAF6; -.
DR BioCyc; EcoCyc:ARTP-MON; -.
DR BioCyc; MetaCyc:ARTP-MON; -.
DR PRO; PR:P0AAF6; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0015426; F:ATPase-coupled polar amino acid-transporter activity; ISM:EcoCyc.
DR GO; GO:0097638; P:L-arginine import across plasma membrane; IDA:EcoCyc.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR030679; ABC_ATPase_HisP-typ.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF00005; ABC_tran; 1.
DR PIRSF; PIRSF039085; ABC_ATPase_HisP; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW Amino-acid transport; ATP-binding; Cell inner membrane; Cell membrane;
KW Membrane; Nucleotide-binding; Reference proteome; Translocase; Transport.
FT CHAIN 1..242
FT /note="Arginine transport ATP-binding protein ArtP"
FT /id="PRO_0000091939"
FT DOMAIN 3..241
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 35..42
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT CONFLICT 94..95
FT /note="WP -> CA (in Ref. 1; CAA60101)"
FT /evidence="ECO:0000305"
FT CONFLICT 121
FT /note="R -> S (in Ref. 1; CAA60101)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 242 AA; 27022 MW; D5B50062E523413A CRC64;
MSIQLNGINC FYGAHQALFD ITLDCPQGET LVLLGPSGAG KSSLLRVLNL LEMPRSGTLN
IAGNHFDFTK TPSDKAIRDL RRNVGMVFQQ YNLWPHLTVQ QNLIEAPCRV LGLSKDQALA
RAEKLLERLR LKPYSDRYPL HLSGGQQQRV AIARALMMEP QVLLFDEPTA ALDPEITAQI
VSIIRELAET NITQVIVTHE VEVARKTASR VVYMENGHIV EQGDASCFTE PQTEAFKNYL
SH
