ID   OMPB2_NEIGO             Reviewed;         348 AA.
AC   P20148;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Major outer membrane protein P.IB;
DE            Short=PIB;
DE            Short=Protein IB;
DE   AltName: Full=Porin;
DE   Flags: Precursor;
GN   Name=porB;
OS   Neisseria gonorrhoeae.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=R10;
RX   PubMed=2825179; DOI=10.1073/pnas.84.22.8135;
RA   Gotschlich E.C., Seiff M.E., Blake M.S., Koomey M.;
RT   "Porin protein of Neisseria gonorrhoeae: cloning and gene structure.";
RL   Proc. Natl. Acad. Sci. U.S.A. 84:8135-8139(1987).
CC   -!- FUNCTION: Serves as a slightly cation selective porin. Major antigen on
CC       the gonococcal cell surface and it may have pathogenic properties in
CC       addition to its porin activity.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; J03017; AAA25500.1; -; Genomic_DNA.
DR   PIR; A39920; A39920.
DR   AlphaFoldDB; P20148; -.
DR   SMR; P20148; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   InterPro; IPR002299; Porin_Neis.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PRINTS; PR00184; NEISSPPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..19
FT   CHAIN           20..348
FT                   /note="Major outer membrane protein P.IB"
FT                   /id="PRO_0000025278"
SQ   SEQUENCE   348 AA;  37173 MW;  4F8473BC713704B1 CRC64;
     MKKSLIALTL AALPVAAMAD VTLYGAIKAG VQTYRSVEHT DGKVSKVETG SEIADFGSKI
     GFKGQEDLGN GLKAVWQLEQ GASVAGTNTG WGNKQSFVGL KGGFGTIRAG SLNSPLKNTG
     ANVNAWESGK FTGNVLEISG MAQREHRYLS VRYDSPEFAG FSGSVQYAPK DNSGSNGESY
     HVGLNYQNSG FFAQYAGLFQ RYGEGTKKIE YDDQTYSIPS LFVEKLQVHR LVGGYDNNAL
     YVSVAAQQQD AKLYGAMSGN SHNSQTEVAA TAAYRFGNVT PRVSYAHGFK GTVDSANHDN
     TYDQVVVGAE YDFSKRTSAL VSAGWLQGGK GADKIVSTAS AVVLRHKF