ID   OMPB4_NEIMI             Reviewed;         331 AA.
AC   P30689;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Major outer membrane protein P.IB;
DE            Short=PIB;
DE            Short=Protein IB;
DE   AltName: Full=Class 3 protein;
DE   AltName: Full=Porin;
DE   Flags: Precursor;
GN   Name=porB;
OS   Neisseria meningitidis serogroup B.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CCUG 18243 / S-3032 / Serogroup B / Serotype 12;
RX   PubMed=1330818; DOI=10.1016/0378-1097(92)90644-4;
RA   Ward M.J., Lambden P.R., Heckels J.E.;
RT   "Sequence analysis and relationships between meningococcal class 3 serotype
RT   proteins and other porins from pathogenic and non-pathogenic Neisseria
RT   species.";
RL   FEMS Microbiol. Lett. 73:283-289(1992).
CC   -!- FUNCTION: Serves as a slightly cation selective porin.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; X65534; CAA46504.1; -; Genomic_DNA.
DR   PIR; S21406; S21406.
DR   AlphaFoldDB; P30689; -.
DR   SMR; P30689; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   InterPro; IPR002299; Porin_Neis.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PRINTS; PR00184; NEISSPPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..19
FT   CHAIN           20..331
FT                   /note="Major outer membrane protein P.IB"
FT                   /id="PRO_0000025284"
SQ   SEQUENCE   331 AA;  35764 MW;  B3AC31A476F126CD CRC64;
     MKKSLIALTL AALPVAAMAD VTLYGTIKAG VETSRSVAHN GAQAASVETG TGIVDLGSKI
     GFKGQEDLGN GLKAIWQVEQ KASIAGTDSG WGNRQSFIGL KGGFGKLRVG RLNSVLKDTG
     DINPWDSKSD YLGVNKIAEP EARLISVRYD SPEFAGLSGS VQYALNDNAG RHNSESYHAG
     FNYKNGGFFV QYGGAYKRHH RVQEDINIEK YQIHRLVSGY DNDALHASVA VQQQDAKLVE
     ENYSHNSQTE VAATLAYRFG NVTPRVSYAH GFRGLVDSAD YTNDYDQVVV GAEYDFSKRT
     SALVSAGWLQ EGKGKNKFVS TAGGVGLRHK F