ID   OMPB_NEIMA              Reviewed;         329 AA.
AC   P57042; A1IPL8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Major outer membrane protein P.IB;
DE            Short=PIB;
DE            Short=Protein IB;
DE   AltName: Full=Class 3 protein;
DE   AltName: Full=Porin;
DE   Flags: Precursor;
GN   Name=porB; OrderedLocusNames=NMA0398;
OS   Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS   Z2491).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122587;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15465 / Z2491;
RX   PubMed=10761919; DOI=10.1038/35006655;
RA   Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA   Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA   Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA   Barrell B.G.;
RT   "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT   Z2491.";
RL   Nature 404:502-506(2000).
CC   -!- FUNCTION: Serves as a slightly cation selective porin.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; AL157959; CAM07688.1; -; Genomic_DNA.
DR   PIR; D81956; D81956.
DR   RefSeq; WP_002247187.1; NC_003116.1.
DR   AlphaFoldDB; P57042; -.
DR   SMR; P57042; -.
DR   EnsemblBacteria; CAM07688; CAM07688; NMA0398.
DR   KEGG; nma:NMA0398; -.
DR   HOGENOM; CLU_038238_4_0_4; -.
DR   OMA; YTSANTM; -.
DR   BioCyc; NMEN122587:NMA_RS02020-MON; -.
DR   Proteomes; UP000000626; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   InterPro; IPR002299; Porin_Neis.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PRINTS; PR00184; NEISSPPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000250"
FT   CHAIN           20..329
FT                   /note="Major outer membrane protein P.IB"
FT                   /id="PRO_0000025280"
SQ   SEQUENCE   329 AA;  35544 MW;  1C7B3EE685B8288A CRC64;
     MKKSLIALTL AALPVAAMAD VTLYGTIKTG VETSRSVEHN GGQVVSVETG TGIVDLGSKI
     GFKGQEDLGN GLKAIWQVEQ KASIAGTDSG WGNRQSFIGL KGGFGKLRVG RLNSVLKDTG
     DINPWDSKSD YLGVNKIAEP EARLISVRYD SPEFAGLSGS VQYALNDNVG RHNSESYHAG
     FNYKNGGFFV QYGGAYKRHQ DVDDVKIEKY QIHRLVSGYD NDALYASVAV QQQDAKLVED
     NSHNSQTEVA ATLAYRFGNV TPRVSYAHGF KGSVDDAKRD NTYDQVVVGA EYDFSKRTSA
     LVSAGWLQEG KGENKFVATA GGVGLRHKF