ID   OMPB_NEISI              Reviewed;         357 AA.
AC   P30692;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Major outer membrane protein P.IB;
DE            Short=PIB;
DE            Short=Protein IB;
DE   AltName: Full=Porin;
DE   Flags: Precursor;
GN   Name=por;
OS   Neisseria sicca.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=490;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CCUG 26474 / CIP 5956 / NCTC 4591;
RX   PubMed=1330818; DOI=10.1016/0378-1097(92)90644-4;
RA   Ward M.J., Lambden P.R., Heckels J.E.;
RT   "Sequence analysis and relationships between meningococcal class 3 serotype
RT   proteins and other porins from pathogenic and non-pathogenic Neisseria
RT   species.";
RL   FEMS Microbiol. Lett. 73:283-289(1992).
CC   -!- FUNCTION: Serves as a slightly cation selective porin.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; X65461; CAA46453.1; -; Genomic_DNA.
DR   PIR; S20736; S20736.
DR   RefSeq; WP_003759347.1; NZ_CP059566.1.
DR   AlphaFoldDB; P30692; -.
DR   SMR; P30692; -.
DR   TCDB; 1.B.1.5.3; the general bacterial porin (gbp) family.
DR   PRIDE; P30692; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   InterPro; IPR002299; Porin_Neis.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PRINTS; PR00184; NEISSPPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..19
FT   CHAIN           20..357
FT                   /note="Major outer membrane protein P.IB"
FT                   /id="PRO_0000025279"
SQ   SEQUENCE   357 AA;  38817 MW;  65E1BC0EAEB5DF83 CRC64;
     MKKSLIALTL AALPVAAMAD VTLYGQVKAG VEVSRTKETV NHVSTKNKTA TEIADFGSRI
     GFKGHEHLSN NLNAIWQVEQ NTSVAGTDKG WGTRESFIGL EGGFGKVRAG KLNTALKDNS
     DSVDPWESSD ANASVLQFGK LKRVDERKVS VRYDSPVFAG FSASAQYQPR DNANPEDKHV
     HDVKTRHSFD LGLNYENSGF FGRYAGTFAK RKVLSDDHLE LFNSNTTLGS GVYKDYQAHR
     LVGGYDANNV LVSVAGQYEG FKADVADAKK NERTEVAVTG GYRMGNVMPR LSYAHGFKAK
     ENGVKQGNSQ YNQVIVGADY DFSKRTSALV SAGWLKEGKG GDKTQSTAGL VGLRHKF