ID   OMPC_ECO57              Reviewed;         367 AA.
AC   Q8XE41;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Outer membrane porin C;
DE   AltName: Full=Outer membrane protein 1B;
DE   AltName: Full=Outer membrane protein C;
DE   AltName: Full=Porin OmpC;
DE   Flags: Precursor;
GN   Name=ompC; OrderedLocusNames=Z3473, ECs3104;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG57350.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36527.1; -; Genomic_DNA.
DR   PIR; B85861; B85861.
DR   PIR; H91016; H91016.
DR   RefSeq; NP_311131.1; NC_002695.1.
DR   RefSeq; WP_000865552.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8XE41; -.
DR   SMR; Q8XE41; -.
DR   IntAct; Q8XE41; 1.
DR   STRING; 155864.EDL933_3381; -.
DR   PRIDE; Q8XE41; -.
DR   EnsemblBacteria; AAG57350; AAG57350; Z3473.
DR   EnsemblBacteria; BAB36527; BAB36527; ECs_3104.
DR   GeneID; 916811; -.
DR   KEGG; ece:Z3473; -.
DR   KEGG; ecs:ECs_3104; -.
DR   PATRIC; fig|386585.9.peg.3238; -.
DR   eggNOG; COG3203; Bacteria.
DR   HOGENOM; CLU_058202_0_0_6; -.
DR   OMA; DNKENSW; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Reference proteome;
KW   Signal; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..367
FT                   /note="Outer membrane porin C"
FT                   /id="PRO_0000025232"
SQ   SEQUENCE   367 AA;  40508 MW;  028A0146D462CAA4 CRC64;
     MKVKVLSLLV PALLVAGAAN AAEVYNKDGN KLDLYGKVDG LHYFSDDKSV DGDQTYMRLG
     FKGETQVTDQ LTGYGQWEYQ IQGNSAENEN NSWTRVAFAG LKFQDVGSFD YGRNYGVVYD
     VTSWTDVLPE FGGDTYGSDN FMQQRGNGFA TYRNTDFFGL VDGLNFAVQY QGKNGSVSGE
     GMTNNGREAL RQNGDGVGGS ITYDYEGFGI GAAVSSSKRT DDQNSPLYIG NGDRAETYTG
     GLKYDANNIY LAAQYTQTYN ATRVGSLGWA NKAQNFEAVA QYQFDFGLRP SLAYLQSKGK
     NLGVINGRNY DDEDILKYVD VGATYYFNKN MSTYVDYKIN LLDDNQFTRD AGINTDNIVA
     LGLVYQF