ID   OMPD_SALTS              Reviewed;         375 AA.
AC   A0A0H3NBQ0;
DT   26-FEB-2020, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 1.
DT   25-MAY-2022, entry version 21.
DE   RecName: Full=Outer membrane porin OmpD {ECO:0000303|PubMed:22538806};
DE   Flags: Precursor;
GN   Name=ompD {ECO:0000303|PubMed:22538806}; OrderedLocusNames=SL1344_1503;
OS   Salmonella typhimurium (strain SL1344).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=216597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA   Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA   Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA   Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA   Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT   "The transcriptional landscape and small RNAs of Salmonella enterica
RT   serovar Typhimurium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
RN   [2]
RP   SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=SL1344;
RX   PubMed=2543631; DOI=10.1128/iai.57.7.2136-2140.1989;
RA   Dorman C.J., Chatfield S., Higgins C.F., Hayward C., Dougan G.;
RT   "Characterization of porin and ompR mutants of a virulent strain of
RT   Salmonella typhimurium: ompR mutants are attenuated in vivo.";
RL   Infect. Immun. 57:2136-2140(1989).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000305}.
CC   -!- SUBUNIT: Homotrimer. Mixed heterotrimers with other porins are also
CC       probable. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000269|PubMed:2543631};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- INDUCTION: Expressed in high osmolarity conditions (at protein level).
CC       {ECO:0000269|PubMed:2543631}.
CC   -!- DISRUPTION PHENOTYPE: Slight decrease in virulence in male BALB/c mice.
CC       {ECO:0000269|PubMed:2543631}.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; FQ312003; CBW17597.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H3NBQ0; -.
DR   SMR; A0A0H3NBQ0; -.
DR   EnsemblBacteria; CBW17597; CBW17597; SL1344_1503.
DR   KEGG; sey:SL1344_1503; -.
DR   PATRIC; fig|216597.6.peg.1670; -.
DR   HOGENOM; CLU_058202_0_0_6; -.
DR   OMA; AVYQHAM; -.
DR   Proteomes; UP000008962; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000255"
FT   CHAIN           35..375
FT                   /note="Outer membrane porin OmpD"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5002616166"
SQ   SEQUENCE   375 AA;  41297 MW;  C70305AC2C721B97 CRC64;
     MRKHAKKIIR IIKMKLKLVA VAVTSLLAAG VVNAAEVYNK DGNKLDLYGK VHAQHYFSDD
     NGSDGDKTYA RLGFKGETQI NDQLTGFGQW EYEFKGNRTE SQGADKDKTR LAFAGLKFAD
     YGSFDYGRNY GVAYDIGAWT DVLPEFGGDT WTQTDVFMTG RTTGVATYRN TDFFGLVEGL
     NFAAQYQGKN DRDGAYESNG DGFGLSATYE YEGFGVGAAY AKSDRTNNQV KAASNLNAAG
     KNAEVWAAGL KYDANNIYLA TTYSETLNMT TFGEDAAGDA FIANKTQNFE AVAQYQFDFG
     LRPSIAYLKS KGKNLGTYGD QDLVEYIDVG ATYYFNKNMS TFVDYKINLL DDSDFTKAAK
     VSTDNIVAVG LNYQF