ID   OMPF_SALTS              Reviewed;         363 AA.
AC   A0A0H3N9T8;
DT   26-FEB-2020, integrated into UniProtKB/Swiss-Prot.
DT   16-SEP-2015, sequence version 1.
DT   03-AUG-2022, entry version 25.
DE   RecName: Full=Outer membrane porin F {ECO:0000303|PubMed:22538806};
DE   AltName: Full=Outer membrane protein F;
DE   AltName: Full=Porin OmpF;
DE   Flags: Precursor;
GN   Name=ompF {ECO:0000303|PubMed:22538806}; OrderedLocusNames=SL1344_0936;
OS   Salmonella typhimurium (strain SL1344).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=216597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL1344;
RX   PubMed=22538806; DOI=10.1073/pnas.1201061109;
RA   Kroger C., Dillon S.C., Cameron A.D., Papenfort K., Sivasankaran S.K.,
RA   Hokamp K., Chao Y., Sittka A., Hebrard M., Handler K., Colgan A.,
RA   Leekitcharoenphon P., Langridge G.C., Lohan A.J., Loftus B., Lucchini S.,
RA   Ussery D.W., Dorman C.J., Thomson N.R., Vogel J., Hinton J.C.;
RT   "The transcriptional landscape and small RNAs of Salmonella enterica
RT   serovar Typhimurium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:E1277-E1286(2012).
RN   [2]
RP   INDUCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=SL1344;
RX   PubMed=2543631; DOI=10.1128/iai.57.7.2136-2140.1989;
RA   Dorman C.J., Chatfield S., Higgins C.F., Hayward C., Dougan G.;
RT   "Characterization of porin and ompR mutants of a virulent strain of
RT   Salmonella typhimurium: ompR mutants are attenuated in vivo.";
RL   Infect. Immun. 57:2136-2140(1989).
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000305}.
CC   -!- SUBUNIT: Homotrimer. Forms mixed heterotrimers with OmpC and with PhoE;
CC       other mixed heterotrimers with other porins are also probable.
CC       {ECO:0000250|UniProtKB:P02931}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000250|UniProtKB:P02931}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:P02931}.
CC   -!- INDUCTION: Not expressed at high osmolarity, probably expressed at low
CC       osmolarity. {ECO:0000269|PubMed:2543631}.
CC   -!- DISRUPTION PHENOTYPE: No effect on virulence in male BALB/c mice.
CC       {ECO:0000269|PubMed:2543631}.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; FQ312003; CBW17032.1; -; Genomic_DNA.
DR   RefSeq; WP_000977713.1; NZ_QASL01000022.1.
DR   AlphaFoldDB; A0A0H3N9T8; -.
DR   SMR; A0A0H3N9T8; -.
DR   EnsemblBacteria; CBW17032; CBW17032; SL1344_0936.
DR   KEGG; sey:SL1344_0936; -.
DR   PATRIC; fig|216597.6.peg.1042; -.
DR   HOGENOM; CLU_058202_0_0_6; -.
DR   OMA; DAIGWTD; -.
DR   BioCyc; SENT216597:SL1344_RS04860-MON; -.
DR   Proteomes; UP000008962; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..363
FT                   /note="Outer membrane porin F"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5002616374"
SQ   SEQUENCE   363 AA;  40048 MW;  F6069B34E9516859 CRC64;
     MMKRKILAAV IPALLAAATA NAAEIYNKDG NKLDLYGKAV GRHVWTTTGD SKNADQTYAQ
     IGFKGETQIN TDLTGFGQWE YRTKADRAEG EQQNSNLVRL AFAGLKYAEV GSIDYGRNYG
     IVYDVESYTD MAPYFSGETW GGAYTDNYMT SRAGGLLTYR NSDFFGLVDG LSFGIQYQGK
     NQDNHSINSQ NGDGVGYTMA YEFDGFGVTA AYSNSKRTND QQDRDGNGDR AESWAVGAKY
     DANNVYLAAV YAETRNMSIV ENTVTDTVEM ANKTQNLEVV AQYQFDFGLR PAISYVQSKG
     KQLNGAGGSA DLAKYIQAGA TYYFNKNMNV WVDYRFNLLD ENDYSSSYVG TDDQAAVGIT
     YQF