ID   OMPU_VIBVU              Reviewed;         340 AA.
AC   Q8DBX0;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Outer membrane protein U;
DE   AltName: Full=Porin OmpU;
DE   Flags: Precursor;
GN   Name=ompU; OrderedLocusNames=VV1_1686;
OS   Vibrio vulnificus (strain CMCP6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=216895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CMCP6;
RA   Rhee J.H., Kim S.Y., Chung S.S., Kim J.J., Moon Y.H., Jeong H., Choy H.E.;
RT   "Complete genome sequence of Vibrio vulnificus CMCP6.";
RL   Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Forms pores that allow passive diffusion of small molecules
CC       across the outer membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; AE016795; AAO10102.1; -; Genomic_DNA.
DR   RefSeq; WP_011079605.1; NC_004459.3.
DR   AlphaFoldDB; Q8DBX0; -.
DR   SMR; Q8DBX0; -.
DR   EnsemblBacteria; AAO10102; AAO10102; VV1_1686.
DR   KEGG; vvu:VV1_1686; -.
DR   HOGENOM; CLU_058202_1_2_6; -.
DR   OMA; YAMAGFQ; -.
DR   Proteomes; UP000002275; Chromosome 1.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   Pfam; PF13609; Porin_4; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..340
FT                   /note="Outer membrane protein U"
FT                   /id="PRO_0000025290"
SQ   SEQUENCE   340 AA;  36754 MW;  9D28DF94B90A5422 CRC64;
     MKKTLIALSV SAAAVATGVN AAELYNQDGT SLDMGGRAEA RLSMKDGKVA DNSRIRLNFL
     GKVEIQDGLY GVGFYEGEFT TADNADGSDL DNRYTYAGLG GKFGEVTYGK NDGALGVITD
     FTDIMAYHGN SAADKIAVAD RVDNMMSYKG QFDALSVKAS YRFADRADSS KNNVDNTYID
     NGKDGYSLSA IYAIGQTGLT LGGGYADQDK SNEYMLAASY TMGDLYFAGV FTDGEKDYGT
     NGDYSHRGFS SVEDYTGYEL AAKYTMGQTV FTTTYNNAET DGYTSTDNFA VDATYYFKPN
     FRGYVSYNFN LLDAGDKIGT STISKADAED ELALGLRYDF