ID   OMPW_VIBCH              Reviewed;         217 AA.
AC   P17266; Q9KL80;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Outer membrane protein W;
DE   Flags: Precursor;
GN   Name=ompW; OrderedLocusNames=VC_A0867;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2336399; DOI=10.1093/nar/18.8.2180;
RA   Jalajakumari M.B., Manning P.A.;
RT   "Nucleotide sequence of the gene, ompW, encoding a 22kDa immunogenic outer
RT   membrane protein of Vibrio cholerae.";
RL   Nucleic Acids Res. 18:2180-2180(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane.
CC   -!- SIMILARITY: Belongs to the OmpW/AlkL family. {ECO:0000305}.
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DR   EMBL; X51948; CAA36210.1; -; Genomic_DNA.
DR   EMBL; AE003853; AAF96765.1; -; Genomic_DNA.
DR   PIR; D82407; D82407.
DR   PIR; S09509; S09509.
DR   RefSeq; NP_233253.1; NC_002506.1.
DR   RefSeq; WP_000814590.1; NZ_LT906615.1.
DR   AlphaFoldDB; P17266; -.
DR   SMR; P17266; -.
DR   STRING; 243277.VC_A0867; -.
DR   DNASU; 2612873; -.
DR   EnsemblBacteria; AAF96765; AAF96765; VC_A0867.
DR   KEGG; vch:VC_A0867; -.
DR   PATRIC; fig|243277.26.peg.3483; -.
DR   eggNOG; COG3047; Bacteria.
DR   HOGENOM; CLU_042505_1_1_6; -.
DR   OMA; DYMLTDN; -.
DR   BioCyc; VCHO:VCA0867-MON; -.
DR   Proteomes; UP000000584; Chromosome 2.
DR   GO; GO:0009279; C:cell outer membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   InterPro; IPR005618; OMPW.
DR   PANTHER; PTHR36920; PTHR36920; 1.
DR   Pfam; PF03922; OmpW; 1.
DR   SUPFAM; SSF56925; SSF56925; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane beta strand.
FT   SIGNAL          1..21
FT   CHAIN           22..217
FT                   /note="Outer membrane protein W"
FT                   /id="PRO_0000020194"
FT   CONFLICT        7
FT                   /note="Missing (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        15..16
FT                   /note="SS -> LA (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        59
FT                   /note="Q -> H (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        79
FT                   /note="A -> R (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        122
FT                   /note="F -> N (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        142
FT                   /note="G -> S (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        147..148
FT                   /note="AG -> NA (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        179
FT                   /note="S -> Y (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        210
FT                   /note="M -> I (in Ref. 1; CAA36210)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   217 AA;  23316 MW;  BF376BB11EF2797B CRC64;
     MKQTICGLAV LAALSSAPVF AHQEGDFIVR AGIASVVPND SSDKVLNTQS ELAVNSNTQL
     GLTLGYMFTD NISFEVLAAT PFSHKISTSG GELGSLGDIG ETKHLPPTFM VQYYFGEANS
     TFRPYVGAGL NYTTFFDESF NGTGTNAGLS DLKLDDSWGL AANVGFDYML NDSWFLNASV
     WYANIETTAT YKAGADAKST DVEINPWVFM IAGGYKF