ID   ONCA_HYDTA              Reviewed;         318 AA.
AC   P22080;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Oncosphere antigen A;
DE   Flags: Fragment;
GN   Name=ONCA;
OS   Hydatigena taeniaeformis (Feline tapeworm) (Taenia taeniaeformis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Hydatigera.
OX   NCBI_TaxID=6205;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2052033; DOI=10.1016/0166-6851(91)90035-5;
RA   Cougle W.G., Lightowlers M.W., Bogh H.O., Rickard M.D., Johnson K.S.;
RT   "Molecular cloning of Taenia taeniaeformis oncosphere antigen genes.";
RL   Mol. Biochem. Parasitol. 45:137-146(1991).
CC   -!- MISCELLANEOUS: ONCA and ONCB are the primary targets of protective
CC       antibody responses.
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DR   EMBL; M38397; AAA63536.1; -; mRNA.
DR   AlphaFoldDB; P22080; -.
DR   SMR; P22080; -.
DR   Proteomes; UP000046396; Genome Assembly.
DR   CDD; cd00063; FN3; 2.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   Pfam; PF00041; fn3; 1.
DR   SMART; SM00060; FN3; 2.
DR   SUPFAM; SSF49265; SSF49265; 2.
DR   PROSITE; PS50853; FN3; 3.
PE   2: Evidence at transcript level;
KW   Repeat.
FT   CHAIN           <1..318
FT                   /note="Oncosphere antigen A"
FT                   /id="PRO_0000058048"
FT   DOMAIN          6..103
FT                   /note="Fibronectin type-III 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   DOMAIN          109..207
FT                   /note="Fibronectin type-III 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   DOMAIN          211..308
FT                   /note="Fibronectin type-III 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
FT   NON_TER         1
SQ   SEQUENCE   318 AA;  35509 MW;  20A530338B4CEDE4 CRC64;
     EFRASIPQNV QIEAIDPHTA RMTWDPPAKS YGSIIGYTIQ WSTDDLWLEQ VKVASDNSYD
     FKDLQSQQTI VASILAHHRP DTSVKFEYIG TRSTPVKVTT PLPSRVMKKP SFRATYCEDL
     EELDMLIHDP EEVVGMFGGF EVLMRAGDAE LLKSWQSVVN LTAEERRYKL KGLVPSLPYA
     VTVRGVALPS RRFSELAEPV HFKISRAEQS VPQNVDMQAT DPHTIEMTWD CRPNPTVALL
     ATPSAGVAIT RSSRSLHLAS VQLYTFTGLE PQVSLSASIC VHYKPQKSPN FEYISSFSEV
     VTATTPSVEQ VDFAEGEE