ID   OOSP3_MOUSE             Reviewed;         195 AA.
AC   G5E8D7; B9EIY2;
DT   10-OCT-2018, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Oocyte-secreted protein 3 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=Oosp3 {ECO:0000312|MGI:MGI:2684943};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   TISSUE SPECIFICITY.
RX   PubMed=12237121; DOI=10.1016/s0006-291x(02)02194-0;
RA   Mano H., Nakatani S., Aoyagi R., Ishii R., Iwai Y., Shimoda N., Jincho Y.,
RA   Hiura H., Hirose M., Mochizuki C., Yuri M., Hyock Im R., Funada-Wada U.,
RA   Wada M.;
RT   "IF3, a novel cell-differentiation factor, highly expressed in murine liver
RT   and ovary.";
RL   Biochem. Biophys. Res. Commun. 297:323-328(2002).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Oocyte-specific. {ECO:0000269|PubMed:12237121}.
CC   -!- SIMILARITY: Belongs to the PLAC1 family. {ECO:0000305}.
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DR   EMBL; AC127289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH466534; EDL41438.1; -; Genomic_DNA.
DR   EMBL; BC141228; AAI41229.1; -; mRNA.
DR   CCDS; CCDS29608.1; -.
DR   RefSeq; NP_001028455.2; NM_001033283.2.
DR   AlphaFoldDB; G5E8D7; -.
DR   SMR; G5E8D7; -.
DR   STRING; 10090.ENSMUSP00000064913; -.
DR   GlyGen; G5E8D7; 1 site.
DR   PaxDb; G5E8D7; -.
DR   PRIDE; G5E8D7; -.
DR   Ensembl; ENSMUST00000069760; ENSMUSP00000064913; ENSMUSG00000055933.
DR   GeneID; 225923; -.
DR   KEGG; mmu:225923; -.
DR   UCSC; uc008gsv.1; mouse.
DR   CTD; 112577461; -.
DR   MGI; MGI:2684943; Oosp3.
DR   VEuPathDB; HostDB:ENSMUSG00000055933; -.
DR   eggNOG; ENOG502TESX; Eukaryota.
DR   GeneTree; ENSGT01030000234567; -.
DR   HOGENOM; CLU_1405388_0_0_1; -.
DR   InParanoid; G5E8D7; -.
DR   OMA; ANIQCAQ; -.
DR   OrthoDB; 1449505at2759; -.
DR   PhylomeDB; G5E8D7; -.
DR   TreeFam; TF338479; -.
DR   BioGRID-ORCS; 225923; 2 hits in 73 CRISPR screens.
DR   ChiTaRS; Oosp3; mouse.
DR   PRO; PR:G5E8D7; -.
DR   Proteomes; UP000000589; Chromosome 19.
DR   RNAct; G5E8D7; protein.
DR   Bgee; ENSMUSG00000055933; Expressed in animal zygote and 12 other tissues.
DR   ExpressionAtlas; G5E8D7; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR033222; PLAC1_fam.
DR   PANTHER; PTHR14380; PTHR14380; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..195
FT                   /note="Oocyte-secreted protein 3"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5015091897"
FT   CARBOHYD        102
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CONFLICT        135
FT                   /note="E -> K (in Ref. 3; AAI41229)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   195 AA;  22638 MW;  F983C0B678F52CF1 CRC64;
     MKAFVASGLL LLIFGMWRCS GIEPVSMECD YFTFRVIAKR ALFYPDDLIG PDELLLGASC
     PVTSIRPDEL EFYYDIHSCG TFIQHAFDGT IVNTWLTYMP RNISIYAELQ LQCVIPRISQ
     DELDNKQSSD ECVGESESID VGNLDFHPPP QCWFLVLKRY CIICGHFHFP NNWLIPYHGW
     KDESFQRLWP SLFHR