ID   OOXA_RHIME              Reviewed;         458 AA.
AC   Q92XP4;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Opine oxidase subunit A;
DE            EC=1.-.-.-;
DE   AltName: Full=Octopine oxidase subunit A;
GN   Name=ooxA; OrderedLocusNames=RA1200; ORFNames=SMa2225;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymA (megaplasmid 1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481432; DOI=10.1073/pnas.161294798;
RA   Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA   Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA   Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA   Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA   Long S.R.;
RT   "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT   meliloti pSymA megaplasmid.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Oxidative cleavage of octopine into L-arginine and pyruvate.
CC       {ECO:0000250}.
CC   -!- PATHWAY: Opine metabolism; octopine degradation.
CC   -!- SUBUNIT: Heterodimer of a subunit A and a subunit B. {ECO:0000250}.
CC   -!- SIMILARITY: To T-protein and to dimethylglycine dehydrogenase.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006469; AAK65858.1; -; Genomic_DNA.
DR   PIR; H95411; H95411.
DR   RefSeq; NP_436446.1; NC_003037.1.
DR   RefSeq; WP_010968148.1; NC_003037.1.
DR   AlphaFoldDB; Q92XP4; -.
DR   SMR; Q92XP4; -.
DR   EnsemblBacteria; AAK65858; AAK65858; SMa2225.
DR   GeneID; 61599937; -.
DR   KEGG; sme:SMa2225; -.
DR   PATRIC; fig|266834.11.peg.1255; -.
DR   HOGENOM; CLU_030705_1_0_5; -.
DR   OMA; GWCQGRM; -.
DR   UniPathway; UPA00737; -.
DR   Proteomes; UP000001976; Plasmid pSymA.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019469; P:octopine catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.10.10.1100; -; 1.
DR   Gene3D; 3.50.50.60; -; 2.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR017224; Opine_Oxase_asu/HCN_bsu.
DR   InterPro; IPR041117; SoxA_A3.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PIRSF; PIRSF037495; Opine_OX_OoxA/HcnB; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase; Plasmid; Reference proteome.
FT   CHAIN           1..458
FT                   /note="Opine oxidase subunit A"
FT                   /id="PRO_0000058050"
SQ   SEQUENCE   458 AA;  48410 MW;  2E61911C377946FE CRC64;
     MSLWDAIVIG AGPAGIGASG LLAENGAKVL VIDEAPGPGG QIWRGVEDVS DARARILGSD
     YLAGRDEVRR LRASGAELSF ETQAWRVEPE GTVWLKDSHG IRRERGRRLL IATGAMERPC
     PLDGWTLPGV TTVGGLQILL KREGMLPGGP LVLIGTGPLF YLFAAQCLAA GMRDLSLIDT
     AAAGAIVSAL RHVPAALTGK GPSYLIKGLK LLWMLRRAGV DIYNHSGDLR IKSAADGLEV
     HFRMREVEHR LSASHVGLHE GVIPETHLPR ALGCRMHWSE AGGAFHPHRD IHLQSSVAGV
     YIAGDAGGIG GATVALLEGR LAAMGILASL GRPIDELLLR ATRRDRAAHL AARPLLDHLY
     QPSPAILTPA DGVLACRCEE VTCGEIRAAL RAGCAGPNQV KAFLRCGMGP CQGRMCGMTL
     TSLAASTHDI SMGDAGFLTI RPPLRPISLG EVADLVEP